Open access · Peer reviewed · No APCs
Research ArticleAsian Journal of Biological and Life SciencesVol. 13 | Issue 1 | 2026 | pp. 100–108Open access
A Comparative Study on the in vitro Cytotoxicity and Anti-Cancer Properties of Gold Nanoparticles Derived from Elettaria cardamomum
- 1,
- 1*
- 1 Department of Biochemistry, Kongunadu Arts and Science College (Autonomous), G.N. Mills P.O, Coimbatore, Tamil Nadu, INDIA.
Published in Asian Journal of Biological and Life Sciences
Correspondence: Ramasamy Thanghavelu Narendhirakannan
Department of Biochemistry, Kongunadu Arts and Science College (Autonomous), G.N. Mills P.O, Coimbatore, Tamil Nadu, INDIA.
Email: rtnaren@kongunaducollege.ac.in
Copyright: © 2026 Manuscript Technomedia. This is an open access article.
- Published:
- Aug 17, 2026
- Received:
- Jan 15, 2024
- Accepted:
- Apr 21, 2024
How to cite
Meladom, S. K., & Narendhirakannan, R. T. (2026). A Comparative Study on the in vitro Cytotoxicity and Anti-Cancer Properties of Gold Nanoparticles Derived from Elettaria cardamomum. Asian Journal of Biological and Life Sciences, 13(1), 100–108. https://doi.org/10.5530/ajbls.2024.13.14
Abstract
Aim: This study scrutinizes the anti-cancer potential of gold nanoparticles derived from Elettaria cardamomum pods and seeds. Materials and Methods: The biosynthesized nanoparticles underwent thorough characterization via UV Vis, FTIR, SEM and EDX analyses. Utilizing the MTT assay, cytotoxicity and anti-cancer efficacy against L929 (normal fibroblast) and Colon cancer cell lines (HT-29 and SW480) cell lines were assessed. Results: Notably, the IC50 values for pod and seed-based nanoparticles were determined as 156.12 μg/mL and 48.771 μg/mL, respectively, against L929 cells. Strikingly, Elettaria cardamomum pod-based nanoparticles demonstrated superior anti-cancer potential against HT-29 and SW480 cell lines compared to seed-based counterparts. Conclusion: Therefore, this study suggests the potential therapeutic utility of greensynthesized gold nanoparticles from Elettaria cardamomum pods as an innovative approach for treating colorectal cancer.
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Article metadata
| Title | A Comparative Study on the in vitro Cytotoxicity and Anti-Cancer Properties of Gold Nanoparticles Derived from Elettaria cardamomum |
|---|---|
| Authors | Sowmya Kizheka Meladom; Ramasamy Thanghavelu Narendhirakannan |
| Affiliations | Department of Biochemistry, Kongunadu Arts and Science College (Autonomous), G.N. Mills P.O, Coimbatore, Tamil Nadu, INDIA. |
| Corresponding author | rtnaren@kongunaducollege.ac.in |
| Journal | Asian Journal of Biological and Life Sciences |
| Volume / Issue | Vol. 13, Issue 1 (2026) |
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