Open access · Peer reviewed · No APCs
research-articleAsian Journal of Biological and Life SciencesVol. 14 | Issue 2 | 2014 | pp. 426–433Open access
Molecular Docking Studies: Hepatitis C Viral-RNA-Dependent RNA Polymerase (RdRp) Inhibitory Activity of Siddha Herbal Formulation Sittramutti khirutham (SK)
- 1,
- 2,
- 3,
- 1
- 1 Department of Siddhar Yoga Maruthuvam, Government Siddha Medical College, Chennai, Tamil Nadu, INDIA.
- 2 Department of Gunapadam, National Institute Siddha, Chennai, Tamil Nadu, INDIA.
- 3 Department of Nanju Maruthuvam, National Institute Siddha, Chennai, Tamil Nadu, INDIA.
Published in Asian Journal of Biological and Life Sciences
Correspondence: Dr. Medini Elanchezhian PG Scholar, Department of Siddhar Yoga Maruthuvam, Government Siddha Medical College, Chennai-600106, Tamil Nadu, INDIA. Email: drmedini22@gmail.com
Copyright: © 2014 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2014
- Received:
- Feb 7, 2025
- Accepted:
- Jun 24, 2025
How to cite
Elanchezhian, M., Ramasamy, S., Balasubramani, A., & Chidambaram, L. (2014). Molecular Docking Studies: Hepatitis C Viral-RNA-Dependent RNA Polymerase (RdRp) Inhibitory Activity of Siddha Herbal Formulation Sittramutti khirutham (SK). Asian Journal of Biological and Life Sciences, 14(2), 426–433. https://doi.org/10.5530/ajbls.20251508
Abstract
Background: Docking studies of Sittramutti khirutham (SK) compounds against HCV RdRp (PDB:3MWV) were performed to evaluate inhibitory potential. Results: Compounds such as Curcumin, Maslinic acid, Arjungenin, Andrograpanin, Andrographolide, and Epiafzelechin showed 2–3 interactions with active residues, indicating promising RdRp inhibition. Conclusion: Docking suggests SK compounds may inhibit HCV RdRp and warrant further pharmacological validation.
Keywords
Article metadata
| Title | Molecular Docking Studies: Hepatitis C Viral-RNA-Dependent RNA Polymerase (RdRp) Inhibitory Activity of Siddha Herbal Formulation Sittramutti khirutham (SK) |
|---|---|
| Authors | Medini Elanchezhian; Suresh Ramasamy; Abarna Balasubramani; Lakshmanaraj Chidambaram |
| Affiliations | Department of Siddhar Yoga Maruthuvam, Government Siddha Medical College, Chennai, Tamil Nadu, INDIA.; Department of Gunapadam, National Institute Siddha, Chennai, Tamil Nadu, INDIA.; Department of Nanju Maruthuvam, National Institute Siddha, Chennai, Tamil Nadu, INDIA. |
| Corresponding author | drmedini22@gmail.com |
| Journal | Asian Journal of Biological and Life Sciences |
| Volume / Issue | Vol. 14, Issue 2 (2014) |
Also in this issue
- Nutraceuticals in Viral Infections: A Comprehensive Review on the Natural Occurrence and Therapeutic Potential of Resveratrol, Quercetin, and N-Acetyl Cysteinepp. 222–227
- Health and Nutrition Problems Among Women in Kerala-A Reviewpp. 228–234
- Artificial Intelligence in Pharmaceutical Regulatory Affairs: An Introductionpp. 235–239
- A Comprehensive Review on Ethno-phytopharmacological Profile of Medicinal Plant Pedalium murexpp. 240–244
- A Review on Ethnobotanical Insights into the Medicinal Potential in District of Himachal Pradesh, Indiapp. 245–258
Readers Also Viewed
Development and Validation of UV/visible Spectrophotometric Method for Estimation of Piroxicam from Bulk and Formulation
Sandip Mohan Honmane, Kunal Rajaram Yadav, Yuvraj Dilip Dange
Apr 23, 2025
Effects of Artificial Intelligence on Academic Performance of Library and Information Science University Students: A Meta-Analysis (2023-2025)
Kayode Sunday John Dada
Aug 6, 2026
Bridging Innovation and Impact: A Multidisciplinary Approach to Contemporary Research Challenges
Mueen Ahmed KK
Aug 11, 2026