Original ArticleFree Radicals and AntioxidantsVol. 12 | Issue 2 | 2022 | pp. 70–73Open access
The Rat Fallopian Tubes after Erythropoietin Process
- 1*,
- 2,
- 3,
- 4,
- 5,
- 5,
- 6
- 1 Department of Gynecology, Anticancer Hospital of Thessaloniki “Theageneio”, Thessaloniki, HELLAS (GREECE).
- 2 Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens University, Athens, Attiki, HELLAS (GREECE).
- 3 Department of Biological Chemistry, Athens University, Athens, Attiki, HELLAS (GREECE).
- 4 Department of Surgery, Ippokrateion General Hospital, Athens University, Athens, Attiki, HELLAS (GREECE).
- 5 Experimental Research Centre, ELPEN Pharmaceuticals, S.A. Inc., Co., Pikermi, Attiki, HELLAS (GREECE).
- 6 Experimental, Educational and Research Center, ELPEN, European University Cyprus, School of Medicine, CYPRUS.
Published in Free Radicals and Antioxidants
Correspondence: C Τsompos
Department of Gynecology, Anticancer Hospital of Thessaloniki “Theageneio”, Thessaloniki, HELLAS (GREECE).
Email: constantinos1tsompos@gmail.com
Copyright: © 2022 Manuscript Technomedia. This is an open access article.
- Published:
- Dec 17, 2022
- Received:
- Oct 23, 2022
- Accepted:
- Dec 5, 2022
How to cite
Τsompos, C., Panoulis, C., Triantafyllou, A., Zografos, C., Gerakis, E., Gerakis, S., & Papalois, A. (2022). The Rat Fallopian Tubes after Erythropoietin Process. Free Radicals and Antioxidants, 12(2), 70–73. https://doi.org/10.5530/fra.2022.2.12
Abstract
Aim: The capability of erythropoietin (EPO) as antioxidant is exported by the results of 2 preliminary studies, totally evaluating 4 histologic variables of endosalpingeal edema (EE) and oviductal congestion (OC) of the first one and endosalpingeal karyorrhexis (EK) and salpingitis (S) of the other one. Materials and Methods: The antioxidant capability was evaluated upon the 60th reperfusion min (for groups called A and C) and upon the 120th reperfusion min (for groups called B and D). The groups A and B were placebo ones, whereas the groups C and D included EPO as antioxidant. Results: The first pillar study showed that EPO has an oxidant non-significant potency for EE and OC together (p-values=0.5971); grade: “without lesions” alterations 0.0363636 [-0.1017439 - 0.1744712]. The second pillar study showed also an oxidant non-significant potency for EK and S; grade: “without lesions” alterations 0.0090909 [-0.0339659 - 0.0521478] (p-values=0.6715). The 2 above studies were added trying to calculate a common diagnostic value for all the four variables. Conclusion: EPO as antioxidant is a significant recessing agent for the total of the 4 histologic variables; grade: “without lesions” alterations score 0.0136364 [-0.0887489+0.0614762] (p-value=0.7153).
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Article metadata
| Title | The Rat Fallopian Tubes after Erythropoietin Process |
|---|---|
| Authors | C Τsompos; C Panoulis; A Triantafyllou; CG Zografos; E Gerakis; S Gerakis; A Papalois |
| Affiliations | Department of Gynecology, Anticancer Hospital of Thessaloniki “Theageneio”, Thessaloniki, HELLAS (GREECE).; Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens University, Athens, Attiki, HELLAS (GREECE).; Department of Biological Chemistry, Athens University, Athens, Attiki, HELLAS (GREECE).; Department of Surgery, Ippokrateion General Hospital, Athens University, Athens, Attiki, HELLAS (GREECE).; Experimental Research Centre, ELPEN Pharmaceuticals, S.A. Inc., Co., Pikermi, Attiki, HELLAS (GREECE).; Experimental, Educational and Research Center, ELPEN, European University Cyprus, School of Medicine, CYPRUS. |
| Corresponding author | constantinos1tsompos@gmail.com |
| Journal | Free Radicals and Antioxidants |
| Volume / Issue | Vol. 12, Issue 2 (2022) |
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