Assessment of Nigella Sativa Induced Adverse Drug Reactions

SM, Jaffar; KB, Chandrasekhar; RY, Padmanabha; S, Bushra

Association of Pharmaceutical Teachers of IndiaIndian Journal of Pharmacy PracticeVol. 6 | Issue 2 | 0201 | pp. 34–37Open access

Assessment of Nigella Sativa Induced Adverse Drug Reactions

¹^*,
²,
¹,
³

¹ Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh – 515721.
² Department of Chemistry, JNTU (a), Anantapur, Andhra Pradesh – 515002.
³ Ayurvedic Physician, Nisa Clinic, M M Road, Adoni, Andhra Pradesh – 518301.

Correspondence: Jaffar SM
Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh – 515721.
Email: jaffar909@yahoo.com

Copyright: © 0201 Manuscript Technomedia. This is an open access article.

Published:: Apr 10, 201
Received:: May 10, 2013
Accepted:: Jun 17, 2013

How to cite

SM, J., KB, C., RY, P., & S, B. (0201). Assessment of Nigella Sativa Induced Adverse Drug Reactions. Indian Journal of Pharmacy Practice, 6(2), 34–37.

Abstract

Objective: Monitoring of Adverse Drug Reactions (ADRs) with intake of Nigella sativa was carried out in a primary care Ayurvedic hospital. Patients were counseled and information regarding their medical and medication history was taken. Methodology: The people who were using Nigella sativa as drug were followed for a period of 6 months prospectively. Naranjo's algorithm, WHO probability scale, Modified Hartwig and Seigel scale and Modified Shumock and Thornton scales were employed to assess the Causality, Severity and Preventability of the ADRs. Results: At the end of the study 22 ADRs were observed with the usage of Nigella sativa for the maintenance of normal health. Among the ADRs 45.45% were found Possible and 54.54% were found Probable (Naranjo's algorithm). Conclusion: In assessment of severity level all the ADRs (100%) were mild and definitely preventable. Even with these ADRs, the medication was not discontinued but dose adjustment was done in all the cases.

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Article metadata

Title	Assessment of Nigella Sativa Induced Adverse Drug Reactions
Authors	Jaffar SM; Chandrasekhar KB; Padmanabha RY; Bushra S
Affiliations	Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER), Anantapur, Andhra Pradesh – 515721.; Department of Chemistry, JNTU (a), Anantapur, Andhra Pradesh – 515002.; Ayurvedic Physician, Nisa Clinic, M M Road, Adoni, Andhra Pradesh – 518301.
Corresponding author	jaffar909@yahoo.com
Journal	Indian Journal of Pharmacy Practice
Volume / Issue	Vol. 6, Issue 2 (0201)