Original ArticleInternational Journal of Pharmaceutical InvestigationVol. 10 | Issue 2 | 2020 | pp. 141–145Open access
Antimicrobial Activity of Extracts of Bark of Cinnamomum cassia and Cinnamomum zeylanicum
- 1,
- 1,
- 2*,
- 1
- 1 Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Kedah, MALAYSIA.
- 2 Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Kedah, MALAYSIA.
Published in International Journal of Pharmaceutical Investigation
Correspondence: Subramani Parasuraman
Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Kedah, MALAYSIA.
Email: parasuphd@gmail.com
Copyright: © 2020 Manuscript Technomedia. This is an open access article.
- Published:
- Jun 8, 2020
- Received:
- Mar 28, 2020
- Accepted:
- May 2, 2020
How to cite
Singh, J., Singh, R., Parasuraman, S., & Kathiresan, S. (2020). Antimicrobial Activity of Extracts of Bark of Cinnamomum cassia and Cinnamomum zeylanicum. International Journal of Pharmaceutical Investigation, 10(2), 141–145. https://doi.org/10.5530/ijpi.2020.2.26
Abstract
Objective: To investigate the antimicrobial activities of various solvent extracts of the bark of Cinnamomum cassia and Cinnamomum zeylanicum. Methods: The powdered barks of C. cassia and C. zeylanicum were extracted using methanol, ethanol and acetone. The antimicrobial activity of methanolic, ethanolic and acetone extracts of barks of C. cassia and C. zeylanicum were studied using agar well diffusion method against seven ATCC bacterial species (Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis, Streptococcus pyogenes, Escherichia coli, Salmonella bongori and Pseudomonas aeruginosa). The antimicrobial activity of extracts of C. cassia and C. zeylanicum were compared with gentamycin. Results: The ethanolic and acetone extract of C. cassia and C. zeylanicum showed greater zones of inhibition than methanolic extract. C. zeylanicum inhibited the growth of all seven ATCC strains used in this study whereas, C. cassia inhibited the growth of S. pyogenes, S. aureus, B. cereus, E. faecalis, P. aeruginosa and S. bongori. Gentamycin inhibited the pathogenic group of all ATCC strains used in this study. Conclusion: The ethanolic and acetone extracts of bark of C. Cassia and C. zeylanicum exhibited a broad spectrum of exhibited a broad-spectrum antimicrobial activity.
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Article metadata
| Title | Antimicrobial Activity of Extracts of Bark of Cinnamomum cassia and Cinnamomum zeylanicum |
|---|---|
| Authors | Jasvin Singh; Rasvin Singh; Subramani Parasuraman; Sathasivam Kathiresan |
| Affiliations | Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Kedah, MALAYSIA.; Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Kedah, MALAYSIA. |
| Corresponding author | parasuphd@gmail.com |
| Journal | International Journal of Pharmaceutical Investigation |
| Volume / Issue | Vol. 10, Issue 2 (2020) |
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