Pharm AnalysisJournal of Young PharmacistsVol. 1 | Issue 4 | 2009 | pp. 371–374Open access
Determination of Progesterone in Capsules by High-Performance Liquid Chromatography and UV- Spectrophotometry
- 1*,
- 1,
- 1,
- 2
- 1 Department of Pharmaceutical Analysis, B.R. Nahata Contract Research Centre, Mandsaur, INDIA.
- 2 Department of Pharmaceutics, College of Pharmacy, IPS Academy, Indore, INDIA.
Published in Journal of Young Pharmacists
Correspondence: Maliwal D
Department of Pharmaceutical Analysis, B.R. Nahata Contract Research Centre, Mandsaur, INDIA.
Email: diyampharm@gmail.com
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Dec 18, 2009
How to cite
D, M., P, J., A, J., & V, P. (2009). Determination of Progesterone in Capsules by High-Performance Liquid Chromatography and UV- Spectrophotometry. Journal of Young Pharmacists, 1(4), 371–374. https://doi.org/10.4103/0975-1483.59330
Abstract
The rapid, simple, and accurate chromatographic (high-performance liquid chromatography) and spectrophotometric method for the determination of progesterone in capsule was elaborated. Methanol was found to be a suitable extraction solvent. The samples were chromatographed on Linchrocart C18 column and UV detection at 254 nm. The elution was achieved isocratically with a mobile phase of methanol - water (80:20, v/v). The method was validated for precision, linearity, accuracy, and limit of detection.
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Article metadata
| Title | Determination of Progesterone in Capsules by High-Performance Liquid Chromatography and UV- Spectrophotometry |
|---|---|
| Authors | Maliwal D; Jain P; Jain A; Patidar V |
| Affiliations | Department of Pharmaceutical Analysis, B.R. Nahata Contract Research Centre, Mandsaur, INDIA.; Department of Pharmaceutics, College of Pharmacy, IPS Academy, Indore, INDIA. |
| Corresponding author | diyampharm@gmail.com |
| Journal | Journal of Young Pharmacists |
| Volume / Issue | Vol. 1, Issue 4 (2009) |
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