Open access · Peer reviewed · No APCs
Letter to editorJournal of Young PharmacistsVol. 10 | Issue 2 | 2018 | pp. 241–242Open access
Discovery of a Series of 5-benzylidene-1, 3-thiazolidine-2, 4-dione-linked Chalcone Hybrids as a Novel Class of 5-Lipoxygenase (5-LO) Inhibitors
- 1*,
- 2,
- 3
- 1 Pharmaceutical Chemistry Division, School of Pharmacy, International Medical University, 126, Jln Jalil Perkasa 19, Bukit Jalil, Wilayah Persekutuan, Kuala Lumpur, MALAYSIA.
- 2 Pharmacology Division, Faculty of Pharmacy, Asia Metropolitan University, G-8 Jalan Kemacahaya 11, Taman Kemacahaya, Cheras, Selangor, MALAYSIA.
- 3 Pharmaceutical Chemistry Division, Faculty of Pharmacy, Asia Metropolitan University, G-8 Jalan Kemacahaya 11, Taman Kemacahaya, Cheras, Selangor, MALAYSIA.
Published in Journal of Young Pharmacists
Correspondence: Vasudeva Rao Avupati
Pharmaceutical Chemistry Division, School of Pharmacy, International Medical University, 126, Jln Jalil Perkasa 19, Bukit Jalil, Wilayah Persekutuan, Kuala Lumpur, MALAYSIA.
Copyright: © 2018 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 4, 2018
- Received:
- Oct 19, 2017
- Accepted:
- Dec 9, 2017
How to cite
Avupati, V. R., Rani, Y., & Singh, A. (2018). Discovery of a Series of 5-benzylidene-1, 3-thiazolidine-2, 4-dione-linked Chalcone Hybrids as a Novel Class of 5-Lipoxygenase (5-LO) Inhibitors. Journal of Young Pharmacists, 10(2), 241–242. https://doi.org/10.5530/jyp.2018.10.53
Abstract
In mammals, lipoxygenases (LOXs) are enzymes containing iron that are biological targets for essential fatty acids. These fatty acids are eico sanoids, derived from arachidonic acid, play important roles in im plication and development of multifactorial inflammatory diseases.
Subject
Article metadata
| Title | Discovery of a Series of 5-benzylidene-1, 3-thiazolidine-2, 4-dione-linked Chalcone Hybrids as a Novel Class of 5-Lipoxygenase (5-LO) Inhibitors |
|---|---|
| Authors | Vasudeva Rao Avupati; Yuawa Rani; Ashwinder Singh |
| Affiliations | Pharmaceutical Chemistry Division, School of Pharmacy, International Medical University, 126, Jln Jalil Perkasa 19, Bukit Jalil, Wilayah Persekutuan, Kuala Lumpur, MALAYSIA.; Pharmacology Division, Faculty of Pharmacy, Asia Metropolitan University, G-8 Jalan Kemacahaya 11, Taman Kemacahaya, Cheras, Selangor, MALAYSIA.; Pharmaceutical Chemistry Division, Faculty of Pharmacy, Asia Metropolitan University, G-8 Jalan Kemacahaya 11, Taman Kemacahaya, Cheras, Selangor, MALAYSIA. |
| Journal | Journal of Young Pharmacists |
| Volume / Issue | Vol. 10, Issue 2 (2018) |
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