Examining Restless Leg Syndrome in Chronic Kidney Disease: Comprehensive Analysis

Background: Restless Leg Syndrome (RLS) is frequently associated with Chronic Kidney Disease (CKD), often under diagnosed and inadequately treated. Hence, this study aimed to ascertain the prevalence of CKD-induced RLS, exploring associated factors, pharmacotherapy and its impact on patients' quality of life. Materials and Methods: An observational prospective study conducted at Dhiraj General Hospital, Vadodara, from November 2022 to March 2023 included 246 CKD patients. Screening for RLS symptoms led to further evaluation and treatment in the Neurology department. Patients were re-evaluated after one month to assess treatment outcomes. Results: Analysis of 246 patients revealed a 6.91% prevalence of RLS in CKD. Factors contributing to RLS included anemia, advanced CKD stages and prolonged dialysis. Female gender emerged as a CKD risk factor. Pramipexole, Syndopa and Ropirinole effectively treated RLS in CKD patients. Conclusion: RLS substantially diminishes the quality of life in end-stage renal disease patients. Identification and management of contributing factors hold promise for improving outcomes and quality of life in CKD patients with RLS.