A Clinical Study to assess the Effectiveness of CPPACP (Casein Phosphopeptide-Amorphous calcium phosphate) versus Potassium-nitrate (KNO3) on cervical dentine hypersensitivity

Aim: To assess the effectiveness of 10% CPP-ACP gel (Casein Phosphopeptide-Amorphous calcium phosphate) and Potassium Nitrate (KNO3) on Cervical Dentin Hypersensitivity (CDH). Materials and Methods: 48 Central jail patients aged 18–67 years reporting with dentinal hypersensitivity were randomly assigned to two groups of 24 patients each. Response to air, water jet and tactile stimuli were measured using visual analogue scale initially at baseline and every progressive week till six weeks and responses were recorded using visual analogue scale. Results: CPP-ACP and KNO3 groups, when compared with their relevant baseline values CDH scores reduced at first week (mean VAS scores 3 and 3.2917, for CPPACP and KNO3 respectively). For CPP-ACP group there was significant reduction in CDH score and the difference being statistically significant (p<0.001). CPP-ACP was significantly more effective than the KNO3 (p<0.001) in reducing CDH. Conclusion: Study showed comparison between the two products for treatment dentinal hypersensitivity, benefits were essentially similar, although a trend towards greater effect with CPP-ACP was apparent.