Review ArticlePharmacognosy ResearchVol. 13 | Issue 1 | 2021 | pp. 706–717Open access
Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents
- 1,2,
- 1*,
- 3,
- 4,
- 4
- 1 Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.
- 2 Department of Pharmacognosy, Farooqia College of Pharmacy, Mysore, Karnataka, INDIA.
- 3 Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.
- 4 Department of Pharmacognosy, Sri Adichunchanagiri College of Pharmacy, Faculty of Pharmacy, Adichunchanagiri University, BG Nagara, Mandya, Karnataka, INDIA.
Published in Pharmacognosy Research
Correspondence: Paramakrishnan Nallupillai
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.
Email: nparamakrishnan@jssuni.edu.in
Copyright: © 2021 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 1, 2021
- Received:
- Jul 5, 2024
- Accepted:
- Sep 4, 2024
- DOI:
- 10.5530/pres.16.4.82
How to cite
Rajappa, R. P. M., Nallupillai, P., Krishna, K. L., Ramesh, M. M., & Venkatappa, A. H. (2021). Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents. Pharmacognosy Research, 13(1), 706–717. https://doi.org/10.5530/pres.16.4.82
Abstract
Herbal hepatoprotective drugs are important for managing liver health because they provide complementary or alternative treatments for the various disorders of the liver. This review provides a thorough analysis of the numerous herbal hepatoprotective drugs' studied during the recent years, including their modes of action, suggested dosages, market trends, status of clinical trials and patents. The hepatoprotective properties of these herbal medicinal products are partly attributed to their mechanisms of actions such as antioxidant, anti-inflammatory, enzyme-modulating actions, and regeneration of hepatocytes. The recommended dosages differ based on the particular plant and ailment, highlighting the necessity for individualized treatment plans and more research to achieve the best possible therapeutic results. Patented compositions and polyherbal formulations provide novel treatments with synergistic effects that improve medicinal efficacy. The increased demand for natural treatments and their potential applications in pharmaceutical and nutraceutical fields has resulted in a considerable and expanding market for herbal hepatoprotective agents. Notwithstanding their possible advantages, more investigation is required to clarify mechanisms of action, assess long-term safety and efficacy, and provide uniform standards for clinical application. In general, herbal hepatoprotective drugs are promising approaches to manage liver health; nonetheless, their use necessitates regulatory oversight, quality control procedures, and evidence-based practice.
Keywords
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Article metadata
| Title | Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents |
|---|---|
| Authors | Rajendra Prasad Menasagere Rajappa; Paramakrishnan Nallupillai; Kamsagara Linganna Krishna; Manoj Madanahalli Ramesh; Annegowda Hardur Venkatappa |
| Affiliations | Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.; Department of Pharmacognosy, Farooqia College of Pharmacy, Mysore, Karnataka, INDIA.; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Bannimantap, Mysuru, Karnataka, INDIA.; Department of Pharmacognosy, Sri Adichunchanagiri College of Pharmacy, Faculty of Pharmacy, Adichunchanagiri University, BG Nagara, Mandya, Karnataka, INDIA. |
| Corresponding author | nparamakrishnan@jssuni.edu.in |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 13, Issue 1 (2021) |
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