Open access · Peer reviewed · No APCs
Research ArticlePharmacognosy ResearchVol. 13 | Issue 1 | 2021 | pp. 784–792Open access
Investigating Dioscorea polystachya Starch as a Pharmaceutical Excipient
- 1*,
- 2,
- 3,
- 3,
- 3,
- 4
- 1 School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, INDIA.
- 2 Department of Physiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, INDIA.
- 3 Department of Pharmaceutical Technology, Faculty of Pharmacy, Asian Institute of Medical Science and Technology (AIMST) University, Kedah, MALAYSIA.
- 4 School of Distance Education, Universiti Sains Malaysia, Pulau Pinang, MALAYSIA.
Published in Pharmacognosy Research
Correspondence: Vijayan Venugopal
School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, INDIA.
Email: vijayanv2@gmail.com
Copyright: © 2021 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 1, 2021
- Received:
- Apr 18, 2024
- Accepted:
- Jun 14, 2024
- DOI:
- 10.5530/pres.16.4.90
How to cite
Venugopal, V., Krishnan, J., Feng, L. H., Ni, A. L., Kumar, V., & Raju, G. (2021). Investigating Dioscorea polystachya Starch as a Pharmaceutical Excipient. Pharmacognosy Research, 13(1), 784–792. https://doi.org/10.5530/pres.16.4.90
Abstract
Background: Dioscorea polystachya (DP) starch, a low-cost, abundant, renewable and degradable starch, is being explored as a potential pharmaceutical excipient for drug formulation. Objectives: This study aimed to explore and isolate starch from Dioscorea polystachya and evaluate the excipients' properties.Materials and Methods: To study the phytochemical, physicochemical, morphological, rheological and emulsifying properties.Results: The isolated matter yields 40.5% starch from its dry weight of tubers and contains carbohydrates, moisture, lipids, nitrogen and various minerals. DP starch has 22.58±0.22% amylose and exhibits a non-Newtonian flow behaviour. The emulsifying capacity improved with the increasing starch concentration and provided significant emulsion stability through different oil ratios to polysaccharide solution. It showed an excellent foaming ability; however, foam stability gradually reduced over time .Conclusion: These findings indicate that Dioscorea polystachya starch provides significant excipient properties so that it could be used as an excipient in the pharmaceutical industry.
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Article metadata
| Title | Investigating Dioscorea polystachya Starch as a Pharmaceutical Excipient |
|---|---|
| Authors | Vijayan Venugopal; Jaiganesh Krishnan; Lim Hui Feng; Ang Li Ni; Venkates Kumar; Gunasunderi Raju |
| Affiliations | School of Pharmacy, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, INDIA.; Department of Physiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, INDIA.; Department of Pharmaceutical Technology, Faculty of Pharmacy, Asian Institute of Medical Science and Technology (AIMST) University, Kedah, MALAYSIA.; School of Distance Education, Universiti Sains Malaysia, Pulau Pinang, MALAYSIA. |
| Corresponding author | vijayanv2@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 13, Issue 1 (2021) |
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