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Research ArticlePharmacognosy ResearchVol. 13 | Issue 1 | 2021 | pp. 887–896Open access
Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis
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- 2,
- 3,
- 4,
- 2,
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- 1 Department of Pharmaceutical Chemistry, School of Pharmacy, Guru Nanak Institutions Technical Campus, Ibrahimpattnam, Telangana, INDIA.
- 2 Department of Pharmaceutical Chemistry, Bojjam Narasimhulu Pharmacy College for Women, Saidabad, Hyderabad, Telangana, INDIA.
- 3 Department of Pharmaceutics, Sree Dattha Institute of Pharmacy, Nagarjuna Sagar Road, Sheriguda, Ibrahimpatnam. Telangana, INDIA.
- 4 Department of Pharmaceutical Chemistry, Srikrupa Institute of Pharmaceutical Sciences, Velikatta, Telangana, INDIA.
- 5 Department of Pharmacology, Nalla Narsimha Reddy College of Pharmacy, Chowdariguda, Narapally, Korremula X Road, Hyderabad, Telangana, INDIA.
- 6 Department of Pharmacology, Vijaya College of Pharmacy, Hayathnagar, Thorrur, Hyderabad, Telangana, INDIA.
- 7 Department of Pharmacy, Avanthi Institute of Pharmaceutical Sciences, Cherukupally, Vizianagaram, Andhra Pradesh, INDIA.
Published in Pharmacognosy Research
Correspondence: Sandip Sen
Department of Pharmaceutical Chemistry, School of Pharmacy, Guru Nanak Institutions Technical Campus, Ibrahimpattnam, Telangana, INDIA.
Email: sandipsen2010@gmail.com
Copyright: © 2021 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 1, 2021
- Received:
- Jun 20, 2024
- Accepted:
- Sep 4, 2024
How to cite
Sen, S., Swathi, K., Vishwanath, D., Ravindar, B., Chaitanya, M., Cherukupally, S., Tejasree, S., & Allu, H. V. S. (2021). Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis. Pharmacognosy Research, 13(1), 887–896. https://doi.org/10.5530/pres.16.4.101
Abstract
Background: Historical records indicate that medicinal plants and their components have been utilized for treating diverse conditions since antiquity. Asparagus racemosus, in particular, demonstrates a broad spectrum of therapeutic possibilities. Aim: This study aimed to pinpoint potential bioactive compounds found within the aqueous extract of Asparagus racemosus. Materials and Methods: Gas Chromatography employed to identify the presence of various molecules, while Mass Spectrometry and FTIR analysis validated their molecular structures. The molecule was subjected to thorough scrutiny for its potential as a drug candidate, its biological activity, and its predicted targets using in silico techniques. Results: The aqueous extract stands out as the richest reservoir of carbohydrates and steroidal alkaloids. The molecule Melezitose was found in the highest concentration (37.86%). The identified molecule is a carbohydrate in nature. The computational analysis revealed promising drug-like properties and therapeutic potential for the investigated molecule. Conclusion: It could serve as a viable therapeutic option for addressing multiple disorders.
Keywords
Subject
Article metadata
| Title | Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis |
|---|---|
| Authors | Sandip Sen; Kalepu Swathi; Dubbasi Vishwanath; Bairam Ravindar; Mitta Chaitanya; Srinivas Cherukupally; Shapuram Tejasree; Hema Varaha Santhoshi Allu |
| Affiliations | Department of Pharmaceutical Chemistry, School of Pharmacy, Guru Nanak Institutions Technical Campus, Ibrahimpattnam, Telangana, INDIA.; Department of Pharmaceutical Chemistry, Bojjam Narasimhulu Pharmacy College for Women, Saidabad, Hyderabad, Telangana, INDIA.; Department of Pharmaceutics, Sree Dattha Institute of Pharmacy, Nagarjuna Sagar Road, Sheriguda, Ibrahimpatnam. Telangana, INDIA.; Department of Pharmaceutical Chemistry, Srikrupa Institute of Pharmaceutical Sciences, Velikatta, Telangana, INDIA.; Department of Pharmacology, Nalla Narsimha Reddy College of Pharmacy, Chowdariguda, Narapally, Korremula X Road, Hyderabad, Telangana, INDIA.; Department of Pharmacology, Vijaya College of Pharmacy, Hayathnagar, Thorrur, Hyderabad, Telangana, INDIA.; Department of Pharmacy, Avanthi Institute of Pharmaceutical Sciences, Cherukupally, Vizianagaram, Andhra Pradesh, INDIA. |
| Corresponding author | sandipsen2010@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 13, Issue 1 (2021) |
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