Open access · Peer reviewed · No APCs
Research ArticlePharmacognosy ResearchVol. 16 | Issue 2 | 2026 | pp. 300–304Open access
Solvent Polarity from Different Plant Extracts Deticate the Potential Activity against Infection by Methicillin-Resistant Staphylococcus aureus in Saudi Arabia
- 1,2,3*,
- 1,
- 1,
- 2,3,
- 2,3,
- 1,
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- 1 Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.
- 2 Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA.
- 3 Production of Bio-Products for Industrial Application Research Group, King Abdulaziz University, Jeddah, SAUDI ARABIA.
- 4 Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, SAUDI ARABIA.
- 5 Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, EGYPT.
- 6 Biochemistry Department, Faculty Of Science, Ain Shams University, Cairo, EGYPT.
Published in Pharmacognosy Research
Correspondence: Taha A. Kumosani
Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA.; Production of Bio-Products for Industrial Application Research Group, King Abdulaziz University, Jeddah, SAUDI ARABIA.
Email: tkumosani@gmail.com
Copyright: © 2026 Manuscript Technomedia. This is an open access article.
- Published:
- Aug 14, 2026
- Received:
- Oct 19, 2023
- Accepted:
- Dec 18, 2023
- DOI:
- 10.5530/pres.16.2.38
How to cite
Kumosani, T. A., Alshehri, S. H., Eissa, F. A., Barbour, E. K., Yaghmoor, S. S., Albogami, T. J., Sunble, S. N., Abdelnapy, T. A., & Moselhy, S. S. (2026). Solvent Polarity from Different Plant Extracts Deticate the Potential Activity against Infection by Methicillin-Resistant Staphylococcus aureus in Saudi Arabia. Pharmacognosy Research, 16(2), 300–304. https://doi.org/10.5530/pres.16.2.38
Abstract
Background: Skin infection by Methicillin-Resistant Staphylococcus aureus (MRSA) is a common disease in Saudi Arabia. This bacterium is resistance to Methicillin and other antibiotics. Skin and soft tissue are the greatest common infected areas by these strains include abscesses, wound infections and other diseases. Materials and Methods: This study evaluated the in vitro antibacterial action of different plants extracts using different solvents from Saudi Arabia against MRSA. Different Plants were extracted by different solvents: methanol, chloroform and n-hexane. Agar well diffusion method was used to determine antibacterial efficacy with 100 μL (5 mg /0.5 mL) of plant extracts. Results: Minimum inhibitory concentration was determined on plant extracts that showed high effectiveness against MRSA. Conclusion: The obtained from Gas chromatography/mass spectrum analysis of the most active four plants, revealed the active volatile oils and flavonoids contents of Artemisia monosperma, Mentha longifolia, Vernonia schimperi and Rumex nervosu have antibacterial activity against MRSA. These plants demonstrate promising anti-MRSA potential.
Keywords
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Article metadata
| Title | Solvent Polarity from Different Plant Extracts Deticate the Potential Activity against Infection by Methicillin-Resistant Staphylococcus aureus in Saudi Arabia |
|---|---|
| Authors | Taha A. Kumosani; Sharifah H. Alshehri; Fatma A. Eissa; Elie K. Barbour; Soonham S. Yaghmoor; Turkyah J. Albogami; Sultan N. Sunble; Tarek A. Abdelnapy; Said S. Moselhy |
| Affiliations | Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA.; Production of Bio-Products for Industrial Application Research Group, King Abdulaziz University, Jeddah, SAUDI ARABIA.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, SAUDI ARABIA.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, EGYPT.; Biochemistry Department, Faculty Of Science, Ain Shams University, Cairo, EGYPT. |
| Corresponding author | tkumosani@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 16, Issue 2 (2026) |
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