LCMS-Based Phytochemical Screening of Albizzia lebbeck

Background and Objectives

Potential antidepressant properties are shown by the ethanolic extract of Albizzia lebbeck (L.), a member of the Fabaceae family. Triterpenes, glycosides, saponins, flavonoids, and indole alkaloids are among the many phytoconstituents that are abundant in the plant. Numerous pharmacological responses, including anti-inflammatory, antioxidant, antiepileptic, anticonvulsant, and antifungal, are highlighted in a review of the literature. A wide range of semi-polar components and important secondary metabolites are responsible for the effects that have been reported, these bioactive components might have therapeutic value in the treatment of depression.

Materials and Methods

After being verified, the plant samples were extracted using ethanol and methanol, examined phytochemically, and then examined using LC-MS. The extracts' antioxidant activity was assessed by the use of DPPH, Assessments for scavenging superoxide anion and hydroxyl group activists

Results

Several Flavonoids, alkaloids, carbolic acid, steroids, tannic acid, glycosides, and saponins are examples of phytochemicals, were examined by the phytochemical Analysis in the ethanolic (AL) and ethanolic extracts. 58 and 81 chemicals were found in ALEN, ALMN, respectively, by LC-MS analysis. Albizzia lebbeck showed greater radical scavenging activity, as indicated by IC₅₀ values, even though the data showed that both extracts had strong antioxidant qualities.

Conclusion

According to these results, Albizzia lebbeck (L.) may contain bioactive substances and be a useful source of organic antioxidants for medicinal purposes. This study for future investigations to isolate and discover new chemicals that may have uses in medication development and therapy.