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Original ArticlePharmacognosy ResearchVol. 18 | Issue 3 | 2026 | pp. 764–770Open access
Free Radical Scavenging Activity and its Embryonic Toxicology Effect of Justicia betonica Leaves Mediated Iron Oxide Nanoparticles
- 1,
- 2,
- 1*,
- 1
- 1 Department of Anatomy, Nanobiomedicine Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, INDIA.
- 2 Department of Pharmacology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, INDIA.
Published in Pharmacognosy Research
Correspondence: Rajeshkumar Shanmugam
Department of Anatomy, Nanobiomedicine Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, INDIA.
Email: rajeshkumars.sdc@saveetha.com
Copyright: © 2026 Manuscript Technomedia. This is an open access article.
- Published:
- May 5, 2026
- Received:
- Jan 2, 2026
- Accepted:
- Apr 27, 2026
How to cite
Govindharaj, S., Sundaram, K. S., Shanmugam, R., & Sankaran, Y. (2026). Free Radical Scavenging Activity and its Embryonic Toxicology Effect of Justicia betonica Leaves Mediated Iron Oxide Nanoparticles. Pharmacognosy Research, 18(3), 764–770. https://doi.org/10.5530/pres.20260116
Abstract
Background
An important milestone in the use of nanoscience and nanotechnology is the development of a dependable and environmentally acceptable green method for the manufacture of magnetic nanoparticles. Numerous biomedical applications of iron oxide nanoparticles have been verified, including drug transport, magnetic resonance imaging, the identification, diagnosis, and management of diseases like cancer and neurological disorders, as well as low toxicity and biological compatibility.
Aim and Objectives
The aim of the current study was determining the free radicals and embryonic toxicology effects of the Justicia betonica mediated iron oxide nanoparticles.
Materials and Methods
To determine the free radical scavenging assay and their zebra fish embryonic toxicology of Justicia betonica leaves mediated iron oxide nanoparticles.
Results
Concentration based free radicals suppression iron oxide nanoparticles is significant for oxidative stress-related concerns. Zebrafish embryonic toxicology experiments indicated safe concentration range in iron oxide nanoparticles.
Conclusion
According to the results of this study, green produced iron oxide nanoparticles may be a promising source of antioxidant agents with lower toxicity.
Keywords
Subject
Article metadata
| Title | Free Radical Scavenging Activity and its Embryonic Toxicology Effect of Justicia betonica Leaves Mediated Iron Oxide Nanoparticles |
|---|---|
| Authors | Sulochana Govindharaj; Kaavya Shanmuga Sundaram; Rajeshkumar Shanmugam; Yuvabalaji Sankaran |
| Affiliations | Department of Anatomy, Nanobiomedicine Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, INDIA.; Department of Pharmacology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, INDIA. |
| Corresponding author | rajeshkumars.sdc@saveetha.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 18, Issue 3 (2026) |
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