Open access · Peer reviewed · No APCs
EditorialPharmacognosy ResearchVol. 4 | Issue 2 | 2012 | pp. 123–126Open access
In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.
- 1,
- 1,
- 2*
- 1 Department of Pharmacology, Shri Ram Institute of Technology -Pharmacy, Jabalpur, Madhya Pradesh
- 2 Department of Pharmacy, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh, India
Published in Pharmacognosy Research
Correspondence: Gopal Rai
Department of Pharmacy, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh, India
Email: drgopalrai1978@gmail.com
Copyright: © 2012 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2012
How to cite
Yadav, P., Ganeshpurkar, A., & Rai, G. (2012). In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. Pharmacognosy Research, 4(2), 123–126. https://doi.org/10.4103/0974-8490.94738
Abstract
Objective
This study was undertaken to study in vitro H+-K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn.
Materials and Methods
Total phenolic and flavonoid contents from extract was quantified and H+-K+ ATPase inhibition assay was performed in presence of different concentrations of standard (omeprazole) and methanol extract.
Results
Extract showed significant (*P < 0.05) proton pump inhibitory activity in the goat gastric mucosal homogenate which was comparable to standard.
Conclusions
These findings showed that methanolic extract of C. quadrangularis Linn. is potent inhibitor of proton pump.
Keywords
Subject
Article metadata
| Title | In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. |
|---|---|
| Authors | Priyanka Yadav; Aditya Ganeshpurkar; Gopal Rai |
| Affiliations | Department of Pharmacology, Shri Ram Institute of Technology -Pharmacy, Jabalpur, Madhya Pradesh; Department of Pharmacy, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur, Madhya Pradesh, India |
| Corresponding author | drgopalrai1978@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 4, Issue 2 (2012) |
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