Open access · Peer reviewed · No APCs
ORIGINAL ARTICLEPharmacognosy ResearchVol. 6 | Issue 1 | 2014 | pp. 58–61Open access
GC-MS analysis of bio-active compounds in methanolic extract of Lactuca runcinata DC
- 1*,
- 4,
- 2,
- 3
- 1 Departments of Pharmacology
- 2 Pharmaceutical Chemistry
- 3 Biotechnology, Koringa College of Pharmacy, Tallarevu Mandal, Andhra Pradesh
- 4 Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India
Published in Pharmacognosy Research
Correspondence: Lakshmi Kanta Kanthal
Departments of Pharmacology
Email: lkkhaldia@gmail.com
Copyright: © 2014 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2014
How to cite
Kanthal, L. K., Dey, A., Satyavathi, K., & Bhojaraju, P. (2014). GC-MS analysis of bio-active compounds in methanolic extract of Lactuca runcinata DC. Pharmacognosy Research, 6(1), 58–61. https://doi.org/10.4103/0974-8490.122919
Abstract
Background
The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC.
Objective
The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata.
Materials and Methods
Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientific Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II.
Results
The phytochemical tests showed the presence of alkaloids, cardiac glycosides, flavonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identified representing 84.49% of total methanolic extract composition.
Conclusion
From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.
Keywords
Subject
Article metadata
| Title | GC-MS analysis of bio-active compounds in methanolic extract of Lactuca runcinata DC |
|---|---|
| Authors | Lakshmi Kanta Kanthal; Akalanka Dey; K. Satyavathi; P. Bhojaraju |
| Affiliations | Departments of Pharmacology; Pharmaceutical Chemistry; Biotechnology, Koringa College of Pharmacy, Tallarevu Mandal, Andhra Pradesh; Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India |
| Corresponding author | lkkhaldia@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 6, Issue 1 (2014) |
Also in this issue
- The hypoglycemic effect of the aqueous extract of the fruits of Balanites aegypticea in Alloxan-induced diabetic ratspp. 1–5
- Comparative study to evaluate the anti-viral efficacy of Glycyrrhiza glabra extract and ribavirin against the Newcastle disease viruspp. 6–11
- Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participantspp. 12–18
- Protection of CCl4-Induced Liver and Kidney Damage by Phenolic Compounds in Leaf Extracts of Cnestis ferruginea (de Candolle)pp. 19–28
- Evaluation of Phyllanthus emblica extract on cold pressor induced cardiovascular changes in healthy human subjectspp. 29–35
Readers Also Viewed
Development and Validation of UV/visible Spectrophotometric Method for Estimation of Piroxicam from Bulk and Formulation
Sandip Mohan Honmane, Kunal Rajaram Yadav, Yuvraj Dilip Dange
Apr 23, 2025
Effects of Artificial Intelligence on Academic Performance of Library and Information Science University Students: A Meta-Analysis (2023-2025)
Kayode Sunday John Dada
Aug 6, 2026
Bridging Innovation and Impact: A Multidisciplinary Approach to Contemporary Research Challenges
Mueen Ahmed KK
Aug 11, 2026