Open access · Peer reviewed · No APCs
ORIGINAL ARTICLEPharmacognosy ResearchVol. 7 | Issue 1 | 2015 | pp. 57–65Open access
The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method
- 1,
- 1,
- 2,
- 1*
- 1 Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd
- 2 Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Published in Pharmacognosy Research
Correspondence: Alireza Nematollahi
Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd
Email: alireza_nemat@yahoo.com
Copyright: © 2015 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2015
How to cite
Kamali, H., Aminimoghadamfarouj, N., Golmakani, E., & Nematollahi, A. (2015). The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method. Pharmacognosy Research, 7(1), 57–65. https://doi.org/10.4103/0974-8490.147209
Abstract
Aim
The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method.
Materials and Methods
Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique.
Results
Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic).
Conclusion
The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.
Keywords
Subject
Article metadata
| Title | The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method |
|---|---|
| Authors | Hossein Kamali; Noushin Aminimoghadamfarouj; Ebrahim Golmakani; Alireza Nematollahi |
| Affiliations | Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd; Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran |
| Corresponding author | alireza_nemat@yahoo.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 7, Issue 1 (2015) |
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