Open access · Peer reviewed · No APCs
Review ArticlePharmacognosy ReviewsVol. 16 | Issue 32 | 2022 | pp. 107–125Open access
Black Cumin: A Review of its Pharmacological Effects and its Main Active Constituent
- 1,
- 2,
- 2,
- 3,
- 4,5,
- 2*
- 1 Department of Refining and Petrochemistry, National Advanced School of Mines and Petroleum Industries, University of Maroua, Kaele, CAMEROON.
- 2 Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, EGYPT.
- 3 Department of Biochemistry and Molecular Biology, Faculty of Science, Egerton University, Egerton, KENYA.
- 4 Laboratory of Natural Product and Organic Synthesis, Department of Chemistry, Faculty of Exact science, University Constantine 1. Constantine, ALGERIA.
- 5 Faculty of Medicine, University Salah Boubnider Constantine 3, Constantine, ALGERIA.
Published in Pharmacognosy Reviews
Correspondence: Gaber El-Saber Batiha
Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, EGYPT.
Email: gaberbatiha@gmail.com
Copyright: © 2022 Manuscript Technomedia. This is an open access article.
- Published:
- Aug 25, 2022
- Received:
- Apr 17, 2022
- Accepted:
- Jun 4, 2022
How to cite
Nyemb, J. N., Shaheen, H., Wasef, L., Nyamota, R., Segueni, N., & Batiha, G. E. S. (2022). Black Cumin: A Review of its Pharmacological Effects and its Main Active Constituent. Pharmacognosy Reviews, 16(32), 107–125. https://doi.org/10.5530/phrev.2022.16.16
Abstract
Black cumin (Nigella sativa) is a well-known medicinal plant and the most exhaustively exploited species of Ranunculaceae family. Nigella sativa seeds have been extensively used as spice in Middle Eastern and Indian cuisine. In addition, they have a long history of use in medicine. This review described the pharmacognostical characteristics, traditional applications and health benefits of N. sativa. The review also described the phytochemical composition and pharmacological properties of N. sativa and its bioactive constituents, in particular thymoquinone, the most abundant active constituent responsible of the effectiveness and pharmacological properties of N. sativa. The review also enumerates pharmacokinetics, possible interaction caused by co-administered drugs, daily dose consumption and toxicity of this medicinal plant. These make the use of N. sativa an interesting approach to the development of new adjuvant or complement treatment.
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Article metadata
| Title | Black Cumin: A Review of its Pharmacological Effects and its Main Active Constituent |
|---|---|
| Authors | Jean Noël Nyemb; Hazem Shaheen; Lamiaa Wasef; Richard Nyamota; Narimane Segueni; Gaber El-Saber Batiha |
| Affiliations | Department of Refining and Petrochemistry, National Advanced School of Mines and Petroleum Industries, University of Maroua, Kaele, CAMEROON.; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, EGYPT.; Department of Biochemistry and Molecular Biology, Faculty of Science, Egerton University, Egerton, KENYA.; Laboratory of Natural Product and Organic Synthesis, Department of Chemistry, Faculty of Exact science, University Constantine 1. Constantine, ALGERIA.; Faculty of Medicine, University Salah Boubnider Constantine 3, Constantine, ALGERIA. |
| Corresponding author | gaberbatiha@gmail.com |
| Journal | Pharmacognosy Reviews |
| Volume / Issue | Vol. 16, Issue 32 (2022) |
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- Edible Vaccines: A Nutritional Substitute for Traditional Immunizationpp. 62–69
- Ethnopharmacological Use, Secondary Metabolites and Biological Activity of Ayapana triplinervis (VAHL) R. M. King and H. Rob.: A Systematic Reviewpp. 70–73
- Universal Aspects of the Genus Mucuna and the Properties Describe of Mucuna urens and Mucuna prurienspp. 74–81
- Experimental Methodologies for the Obtainment of Momordica charantia L. Extracts with Anthelminth Activity: A Reviewpp. 82–89
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