A Systematic Review on Biochemical and Pharmacological Properties of the Active Phytochemicals Present in Aegle marmelos (L).

Aim: Medicinal plant research is becoming increasingly prevalent since it is devoid of pollution, toxins and adverse effects. In recent years, it has come to light that a variety of ailments can be treated with plant-derived compounds from fruits, seeds, leaves, bark, etc. Aegle marmelos (Bael tree) is an important medicinal as well as a sacred tree with diverse therapeutic values. This review is to present current knowledge on the ethnomedicinal applications, nutritional composition, bioactive constituents and pharmacological activity of A. marmelos to validate its therapeutic potential. Materials and Methods: Out of 120 articles identified, 62 met the inclusion criteria, forming the basis for synthesizing data on ethnomedicinal uses, bioactive constituents and pharmacological activities of A. marmelos, contributing to a holistic understanding of its therapeutic potential. The study employed a robust methodology, including a comprehensive literature search across prominent databases using keywords related to Aegle marmelos and also its medicinal properties. Results: These research and review articles provided about the pharmacological properties of A. Marmelos. It has been utilized to treat several health issues in ancient medicinal system, including diarrhea, diabetes, fever, ulcers, inflammations and bacterial infections. The bioactive metabolites including alkaloids, terpenoids, saponins, pectins, steroids, flavonoids, tannins, carotenoids and phenolics. Conclusion: Based on our studies, in vitro as well as in vivo investigations revealed that A. marmelos has therapeutic benefits such as antioxidant, analgesic, anti-inflammatory, antidiarrheal, cardioprotective, anticancer and antimicrobial properties that proved its historical uses.