Open access · Peer reviewed · No APCs
Short communicationFree Radicals and AntioxidantsVol. 3 | Issue 1 | 2013 | pp. 40–42Open access
Radical scavenging ability of glycyrrhizin
- 1*,
- 1,
- 1,
- 1
- 1 Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka 573 0101, Japan.
Published in Free Radicals and Antioxidants
Correspondence: Kimie Imai
Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka 573 0101, Japan.
Email: imai@pharm.setsunan.ac.jp
Copyright: © 2013 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2013
- Received:
- Apr 6, 2013
- Accepted:
- Apr 25, 2013
How to cite
Imai, K., Takagi, Y., Iwazaki, A., & Nakanishi, K. (2013). Radical scavenging ability of glycyrrhizin. Free Radicals and Antioxidants, 3(1), 40–42. https://doi.org/10.1016/j.fra.2013.04.003
Abstract
Glycyrrhizin (Gly), a major constituent of licorice root, has been used for the treatment of chronic liver diseases in Japan. Reports have been contradictory as to whether Gly scavenges hydroxyl radicals and superoxide anion radicals. We examined the radical scavenging abilities of Gly and glycyrrhezic acid (GA), an aglycon of Gly. Gly and GA did not scavenge hydroxyl radicals or superoxide anion radicals, but both scavenged 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, in contrast to previous reports. The scavenging abilities of Gly and GA might play a role in the treatment of chronic liver diseases.
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Subject
Article metadata
| Title | Radical scavenging ability of glycyrrhizin |
|---|---|
| Authors | Kimie Imai; Yushi Takagi; Ayano Iwazaki; Kunio Nakanishi |
| Affiliations | Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka 573 0101, Japan. |
| Corresponding author | imai@pharm.setsunan.ac.jp |
| Journal | Free Radicals and Antioxidants |
| Volume / Issue | Vol. 3, Issue 1 (2013) |
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