Design and Synthesis of Novel Indolizine Analogues as COX-2 Inhibitors: Computational Perspective and in vitro Screening

• Chandrashekharappa Sandeep¹,
• Katharigatta Narayanaswamy Venugopala^2,3*,
• Mohammed A. Khedr^3,4,
• Basavaraj Padmashali^5,6*,
• Rashmi Sanganna Kulkarni⁷,
• Rashmi Venugopala⁸,
• Bharti Odhav²

1. ¹ Institute for Stem Cell Biology and Regenerative Medicine, NCBS, TIFR, GKVK, Bellary Road, Bangalore-560065, INDIA.
2. ² Department of Biotechnology and Food Technology, Durban University of Technology, Durban 4001, SOUTH AFRICA.
3. ³ Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Kingdom of SAUDI ARABIA.
4. ⁴ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Ein Helwan, Cairo 11795, EGYPT.
5. ⁵ Department of Chemistry, Sahyadri Science College (Autonomous), Shimoga 577 203, INDIA.
6. ⁶ Department of Studies and Research in Chemistry, School of Basic Sciences, Rani Channamma University, Belagavi 591 156, Karnataka, INDIA.
7. ⁷ Department of Chemistry, Jain University, Bangalore 560 019, INDIA.
8. ⁸ Department of Public Health Medicine, University of KwaZulu-Natal, Howard College Campus, Durban 4001, SOUTH AFRICA.

Published in Indian Journal of Pharmaceutical Education and Research