Recent Developments on Pharmacological Potential of 1,3,4-Oxadiazole Scaffold

  Heterocyclic compounds represent the important structural key in pharmaceutical medicinal chemistry. In literature, five-membered heterocycles are reported to be a core moiety of various pharmaceutical drugs. 1,3,4-oxadiazole scaffold, among various five-membered heterocycles is an important molecule which attracts various medicinal chemist to develop a novel biologically active molecule. 1,3,4-Oxadiazole is found to bear important pharmacological activities such as anti-diabetic, antimicrobial, anti-cancer, anticonvulsant, antioxidant, anti-Alzheimer’s, anti-inflammatory, antiviral, cardiovascular, anti-tuberculosis, anti-pyretic, insecticidal. This review compiles the biological updates on various compounds containing 1,3,4-oxadiazole as a core moiety from the recent years.