Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug

Panda, Dibya Sundar; Khandai, Madhusmruti

doi:10.5530/ijper.57.3s.82

Original ArticleIndian Journal of Pharmaceutical Education and ResearchVol. 57 | Issue 3s | 2023 | pp. s724–s733Open access

Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug

¹^*,
²

¹ Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.
² Departments of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur, Odisha, INDIA.

Correspondence: Dibya Sundar Panda
Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.
Email: dspanda@ju.edu.sa

Published:: Jul 15, 2023
Received:: Sep 14, 2022
Accepted:: Jun 8, 2023
DOI:: 10.5530/ijper.57.3s.82

How to cite

Panda, D. S., & Khandai, M. (2023). Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug. Indian Journal of Pharmaceutical Education and Research, 57(3s), s724–s733. https://doi.org/10.5530/ijper.57.3s.82

Abstract

Background: Natural biopolymers or hydrogels are explored to sustain release of water-soluble drugs. Materials and Methods: Mucilage was isolated from Salvia hispanica seeds. Gelispheres loaded with Losartan Potassium (LP) were prepared using sodium alginate, pectin and CSM. Results: Isolated mucilage possesses immense properties like consistency and excellent hydration. Developed gelispheres exhibited good mucoadhesion and sustained drug release. Conclusion: Findings advocate the use of mucilage for twice daily losartan potassium sustain release system.

Keywords

Article metadata

Title	Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug
Authors	Dibya Sundar Panda; Madhusmruti Khandai
Affiliations	Department of Pharmaceutics, Pharmacy College, Jouf University, Sakaka, Al-jouf, SAUDI ARABIA.; Departments of Pharmaceutics, Royal College of Pharmacy and Health Sciences, Berhampur, Odisha, INDIA.
Corresponding author	dspanda@ju.edu.sa
Journal	Indian Journal of Pharmaceutical Education and Research
Volume / Issue	Vol. 57, Issue 3s (2023)