Original ArticleInternational Journal of Pharmaceutical InvestigationVol. 14 | Issue 1 | 2023 | pp. 186–190Open access
Effectiveness and Safety of Levonorgestrel Intrauterine Device in Abnormal Uterine Bleeding, Adenomyosis and Perimenopausal Bleeding Patients
- 1,
- 1,
- 1,
- 2,
- 2,
- 2,
- 3,
- 1*
- 1 Department of Pharmacy, Bharat Institute of Technology, Mangalpally, Ibrahimpatnam, Hyderabad, Telangana, INDIA.
- 2 Department of Obstetrics and Gynaecology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, INDIA.
- 3 Department of Pharmacy, Institute of Pharmaceutical Technology, SPMVV, Tirupati, Andhra Pradesh, INDIA.
Published in International Journal of Pharmaceutical Investigation
Correspondence: Arifa Begum SK
Department of Pharmacy, Bharat Institute of Technology, Mangalpally, Ibrahimpatnam, Hyderabad, Telangana, INDIA.
Email: arifabegum@bitpharmacy.org
Copyright: © 2023 Manuscript Technomedia. This is an open access article.
- Published:
- Dec 15, 2023
- Received:
- Jul 27, 2023
- Accepted:
- Oct 23, 2023
- DOI:
- 10.5530/ijpi.14.1.24
How to cite
Jaiswal, A., Srivarshini, M., Reddy, P. A., Sundari, T., Sunkavalli, S., Vandanasetti, R., Begum, S., & SK, A. B. (2023). Effectiveness and Safety of Levonorgestrel Intrauterine Device in Abnormal Uterine Bleeding, Adenomyosis and Perimenopausal Bleeding Patients. International Journal of Pharmaceutical Investigation, 14(1), 186–190. https://doi.org/10.5530/ijpi.14.1.24
Abstract
Background: The Levonorgestrel-releasing intrauterine system was inserted in patients with conditions like Abnormal Uterine Bleeding (AUB), adenomyosis and Perimenopausal Bleeding (PMB). This study aimed to find the effectiveness and safety of the intrauterine device in AUB, adenomyosis and PMB. Materials and Methods: This observational study enrolled 100 patients with AUB, adenomyosis and PMB who had levonorgestrel IUD inserted for treatment between the years 2015 to 2022. The data has been collected from the Department of Obstetrics and Gynecology at Krishna Institute of Medical Sciences, Secunderabad and analyzed based on the Institutional outcome scoring form. The post-insertion responses, expulsion rates and clinical outcomes towards IUD were observed in patients after insertion. Results: The analysis of post-insertion responses showed a significant statistical P value of 0.001 which implies the effectiveness of IUD. This study resulted in a 90% positive clinical outcome which implies the safety of levonorgestrel IUD. The expulsion rate was also very low that was 5 out of 100 patients had the device expelled. Conclusion: The levonorgestrel IUD showed significant positive clinical outcomes in patients with AUB, Adenomyosis and PMB with low expulsion rates and can be considered a good alternative for conservative management of AUB, Adenomyosis, and perimenopausal bleeding.
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Article metadata
| Title | Effectiveness and Safety of Levonorgestrel Intrauterine Device in Abnormal Uterine Bleeding, Adenomyosis and Perimenopausal Bleeding Patients |
|---|---|
| Authors | Aayushi Jaiswal; Mudumba Srivarshini; Patlolla Akshitha Reddy; Tripura Sundari; Sirisha Sunkavalli; Ramya Vandanasetti; Shaheen Begum; Arifa Begum SK |
| Affiliations | Department of Pharmacy, Bharat Institute of Technology, Mangalpally, Ibrahimpatnam, Hyderabad, Telangana, INDIA.; Department of Obstetrics and Gynaecology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, INDIA.; Department of Pharmacy, Institute of Pharmaceutical Technology, SPMVV, Tirupati, Andhra Pradesh, INDIA. |
| Corresponding author | arifabegum@bitpharmacy.org |
| Journal | International Journal of Pharmaceutical Investigation |
| Volume / Issue | Vol. 14, Issue 1 (2023) |
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