Review ArticleInternational Journal of Pharmaceutical InvestigationVol. 15 | Issue 3 | 2025 | pp. 837–848Open access
Nanoscale Formulations for Targeted Drug Delivery: Enhancing Stability, Release Control and Therapeutic Efficacy
- 1,
- 1*,
- 2,
- 3,
- 4,
- 1,
- 1
- 1 Department of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai, Tamil Nadu, INDIA.
- 2 Assistant Professor, Department of Pharmaceutics, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, INDIA.
- 3 Manager Analytical Chemistry, Elixir Medical Corporation, 920 N McCarthy Blvd #100, Milpitas, CA 95035, UNITED STATES.
- 4 Research Scholar, Department of Pharmaceutics, Raffles University, Neemrana, Alwar, Rajasthan, INDIA.
Published in International Journal of Pharmaceutical Investigation
Correspondence: Ramaiyan Velmurugan
Department of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai, Tamil Nadu, INDIA.
Email: velmuruganr.scop@saveetha.com
Copyright: © 2025 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 21, 2025
- Received:
- Nov 17, 2024
- Accepted:
- Mar 7, 2025
How to cite
Ravikumar, L., Velmurugan, R., Jahnavi, P., Vidiyala, P., Kumar, J. P., Rahul, A., & Bhuvaneshwaran, P. (2025). Nanoscale Formulations for Targeted Drug Delivery: Enhancing Stability, Release Control and Therapeutic Efficacy. International Journal of Pharmaceutical Investigation, 15(3), 837–848. https://doi.org/10.5530/ijpi.20250189
Abstract
The present study focuses on the nanoscale formulation technique for pharmacological agent delivery, avoiding the shortcomings of conventional protocols, such as rapid pharmaceutical clearance, limited site-specific accuracy and reduced biological accessibility. The goal of this is that because nanoscale particles can improve stability, control pharmaceutical release and increase penetration, they have emerged as a promising drug delivery technology. Targeted therapies for conditions like septicemia and bronchial asthma can be developed by attaching particular molecular binders to nanoscale particles. This reduces toxicity while maximizing therapeutic efficacy. In summary, this analysis highlights the medicinal delivery potential of nanoscale formulations, including the mechanisms of action of botanical constituents such as flavonoids and triterpenoidal compounds. It also implies that the administration of inflammatory conditions may benefit greatly from the use of nanoscale particles loaded with these compounds.
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Article metadata
| Title | Nanoscale Formulations for Targeted Drug Delivery: Enhancing Stability, Release Control and Therapeutic Efficacy |
|---|---|
| Authors | Lokeshvar Ravikumar; Ramaiyan Velmurugan; Patibandla Jahnavi; Pradeep Vidiyala; J Pavan Kumar; A Rahul; P Bhuvaneshwaran |
| Affiliations | Department of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Saveetha Nagar, Chennai, Tamil Nadu, INDIA.; Assistant Professor, Department of Pharmaceutics, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, INDIA.; Manager Analytical Chemistry, Elixir Medical Corporation, 920 N McCarthy Blvd #100, Milpitas, CA 95035, UNITED STATES.; Research Scholar, Department of Pharmaceutics, Raffles University, Neemrana, Alwar, Rajasthan, INDIA. |
| Corresponding author | velmuruganr.scop@saveetha.com |
| Journal | International Journal of Pharmaceutical Investigation |
| Volume / Issue | Vol. 15, Issue 3 (2025) |
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