Open access · Peer reviewed · No APCs
Original ArticleInternational Journal of Pharmaceutical InvestigationVol. 17 | Issue 1 | 2026 | pp. 300–309Open access
Pareto Analysis-Based Risk Stratification and Prevention Strategies for Adverse Drug Reactions in our Hospital (2022-2025)
- 1*,
- 2,
- 3*,
- 1*
- 1 Department of Pharmacy, Shanghai Second People’s Hospital, Shanghai, CHINA.
- 2 School of Life Sciences and Technology, Northwestern Polytechnical University, Xi’an, Shaanxi, CHINA.
- 3 Department of Stomatology, Northwest Nonferrous Hospital, Xi’an, Shaanxi, CHINA.
Published in International Journal of Pharmaceutical Investigation
Correspondence: Yuanchao Kang
Department of Pharmacy, Shanghai Second People’s Hospital, Shanghai, CHINA.
Email: kyckyc1987@163.com
Copyright: © 2026 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2026
- Received:
- May 16, 2026
- Accepted:
- Sep 8, 2026
How to cite
Kang, Y., Chen, S., Hao, Y., & Lin, Y. (2026). Pareto Analysis-Based Risk Stratification and Prevention Strategies for Adverse Drug Reactions in our Hospital (2022-2025). International Journal of Pharmaceutical Investigation, 17(1), 300–309. https://doi.org/10.5530/ijpi.20270131
Abstract
Background
Adverse Drug Reactions (ADRs) severely affect clinical medication safety, and the Pareto principle is widely applied to identify key risk factors in pharmacovigilance. Systematic retrospective analysis of hospital ADR data helps clarify ADR distribution characteristics.
Objectives
To analyze the epidemiological characteristics of ADRs in a single hospital and screen high-risk factors, so as to provide evidence for rational clinical medication and targeted ADR prevention.
Materials and Methods
A retrospective study was conducted on ADR data reported to the National Adverse Drug Reaction Monitoring System from 2022 to 2025. Basic information of ADRs was statistically organized, and the Pareto principle was utilized to classify key risk indicators.
Results
A total of 567 ADR reports were collected, including 188 severe, 376 common, and 3 newly reported non-serious cases. Hematological disorders, elderly patients (≥60 years), intravenous administration, and combined use of anticancer drugs and traditional Chinese patent medicines were categorized as Category A high-risk factors with prominent cumulative proportions.
Conclusion
Hospital ADRs show obvious clustering characteristics. Targeted intervention and precise management for the confirmed high-risk links can effectively reduce ADR risks and improve clinical medication safety.
Keywords
Subject
Article metadata
| Title | Pareto Analysis-Based Risk Stratification and Prevention Strategies for Adverse Drug Reactions in our Hospital (2022-2025) |
|---|---|
| Authors | Yuanchao Kang; Shizhe Chen; Yanwen Hao; Yan Lin |
| Affiliations | Department of Pharmacy, Shanghai Second People’s Hospital, Shanghai, CHINA.; School of Life Sciences and Technology, Northwestern Polytechnical University, Xi’an, Shaanxi, CHINA.; Department of Stomatology, Northwest Nonferrous Hospital, Xi’an, Shaanxi, CHINA. |
| Corresponding author | kyckyc1987@163.com |
| Journal | International Journal of Pharmaceutical Investigation |
| Volume / Issue | Vol. 17, Issue 1 (2026) |
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