Phytochemical Prospection, Toxicity and Antimicrobial Activity of Mentha arvensis (Labiatae) from Northeast of Brazil

Nascimento, Eidla Mikaelle Maciel do; Rodrigues, Fabíola Fernandes Galvão; Campos, Adriana Rolim; Costa, José Galberto Martins da

doi:10.4103/0975-1483.57066

PharmacognosyJournal of Young PharmacistsVol. 1 | Issue 3 | 2009 | pp. 210–212Open access

Phytochemical Prospection, Toxicity and Antimicrobial Activity of Mentha arvensis (Labiatae) from Northeast of Brazil

¹,
^1,2,
³,
^1,2^*

¹ Departamento de Química-Biológica, Laboratório de Pesquisa de Produtos Naturais, Universidade Regional do Cariri, Rua Cel. Antônio Luiz 1161, Pimenta, 63105-000 Crato-CE, BRASIL.
² Curso de Biomedicina, Faculdade Leão Sampaio, Juazeiro do Norte – Ceará, BRASIL.
³ Vice-Reitoria de Pesquisa e Pós-Graduação, Universidade de Fortaleza, Av. Washington Soares 1321, Edson Queiroz, 60811-905, Fortaleza-CE, BRASIL.

Correspondence: José Galberto Martins da Costa
Departamento de Química-Biológica, Laboratório de Pesquisa de Produtos Naturais, Universidade Regional do Cariri, Rua Cel. Antônio Luiz 1161, Pimenta, 63105-000 Crato-CE, BRASIL.; Curso de Biomedicina, Faculdade Leão Sampaio, Juazeiro do Norte – Ceará, BRASIL.
Email: galberto.martins@gmail.com

Published:: Aug 16, 2009
DOI:: 10.4103/0975-1483.57066

How to cite

Nascimento, E. M. M. D., Rodrigues, F. F. G., Campos, A. R., & Costa, J. G. M. D. (2009). Phytochemical Prospection, Toxicity and Antimicrobial Activity of Mentha arvensis (Labiatae) from Northeast of Brazil. Journal of Young Pharmacists, 1(3), 210–212. https://doi.org/10.4103/0975-1483.57066

Abstract

The present study has been designed with the objective to examine the ethanol extract of Mentha arvensis leaves, in order to evaluate its chemical composition, investigate its in vitro antimicrobial potential against strains of Escherichia coli, Pseudomonas aeruginosa, Shigella fl exineri, Klebsiella pneumoniae and Sthaphylococcus aureus, and Þ nd its toxicity toward Artemia salina and. Phytochemical analysis revealed the presence of catechic tannins, ß avones, ß avonols, xantones, ß avonols, ß avonones and steroids. The antibacterial activity is more signiÞ cant against Sthaphylococcus aureus. In toxicity tests on Artemia salina, the ethanol extract from Mentha arvensis leaves showed LC50 value of 100 µg/mL. These results may justify the popular use of this species as it has antimicrobial activity and demonstrate its signiÞ cant toxic effect on brine shrimp. However, in order to evaluate possible clinical application in therapy of infectious diseases, further studies about the safety and toxicity of isolated compounds are needed.

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Article metadata

Title	Phytochemical Prospection, Toxicity and Antimicrobial Activity of Mentha arvensis (Labiatae) from Northeast of Brazil
Authors	Eidla Mikaelle Maciel do Nascimento; Fabíola Fernandes Galvão Rodrigues; Adriana Rolim Campos; José Galberto Martins da Costa
Affiliations	Departamento de Química-Biológica, Laboratório de Pesquisa de Produtos Naturais, Universidade Regional do Cariri, Rua Cel. Antônio Luiz 1161, Pimenta, 63105-000 Crato-CE, BRASIL.; Curso de Biomedicina, Faculdade Leão Sampaio, Juazeiro do Norte – Ceará, BRASIL.; Vice-Reitoria de Pesquisa e Pós-Graduação, Universidade de Fortaleza, Av. Washington Soares 1321, Edson Queiroz, 60811-905, Fortaleza-CE, BRASIL.
Corresponding author	galberto.martins@gmail.com
Journal	Journal of Young Pharmacists
Volume / Issue	Vol. 1, Issue 3 (2009)