Open access · Peer reviewed · No APCs
PharmacognosyJournal of Young PharmacistsVol. 2 | Issue 2 | 2010 | pp. 130–136Open access
Aqueous Extract of Ficus bengalensis Linn. Bark for Inflammatory Bowel Disease
- 1*,
- 1,
- 2
- 1 Department of Pharmacology, C. K. Pithawala Institute of Pharmaceutical Sciences and Research, Surat-395007, Gujarat, INDIA.
- 2 Department of Pharmacology, Shri Sarvajanik College of Pharmacy, Mahesana, Gujarat, INDIA.
Published in Journal of Young Pharmacists
Correspondence: Patel MA
Department of Pharmacology, C. K. Pithawala Institute of Pharmaceutical Sciences and Research, Surat-395007, Gujarat, INDIA.
Email: hdpharmacology@gmail.com
Copyright: © 2010 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 22, 2010
How to cite
MA, P., PK, P., & MB, P. (2010). Aqueous Extract of Ficus bengalensis Linn. Bark for Inflammatory Bowel Disease. Journal of Young Pharmacists, 2(2), 130–136. https://doi.org/10.4103/0975-1483.63149
Abstract
The present study was designed to evaluate the effects of aqueous extract of Ficus bengalensis Linn. bark (AEFB) on inflammatory bowel disease (IBD). Effects of AEFB were studied on 2, 4, 6-trinitrobenzenesulfonic acid (TNBS, 0.25 ml 120 mg/ml in 50% ethanol intrarectally, on first day only)-induced IBD in rats. Effects of coadministration of prednisolone (2 mg/kg) and AEFB (250, 500 mg/kg) for 21 days were also evaluated. Various physical parameters including body weight, food, and water intake measured on 1st and 21st days. At end of the experiment, various histopathological indexes are assessed. The colon homogenate malondialdehyde (MDA), myeloperoxidase (MPO), superoxide dismutase (SOD), and nitric oxide (NO) levels and % mast cell protection in mesentery were also measured. In our study, we found that AEFB has a significant protective effect in the inflammatory bowel disease as compared to prednisolone in rats.
Keywords
Subject
Article metadata
| Title | Aqueous Extract of Ficus bengalensis Linn. Bark for Inflammatory Bowel Disease |
|---|---|
| Authors | Patel MA; Patel PK; Patel MB |
| Affiliations | Department of Pharmacology, C. K. Pithawala Institute of Pharmaceutical Sciences and Research, Surat-395007, Gujarat, INDIA.; Department of Pharmacology, Shri Sarvajanik College of Pharmacy, Mahesana, Gujarat, INDIA. |
| Corresponding author | hdpharmacology@gmail.com |
| Journal | Journal of Young Pharmacists |
| Volume / Issue | Vol. 2, Issue 2 (2010) |
Also in this issue
- Conflict of Interest in Peer-Reviewed Medical Journals: The World Association of Medical Editors Position on a Challenging Problempp. 113–115
- Studies on In situ Hydrogel: A Smart Way for Safe and Sustained Ocular Drug Deliverypp. 116–120
- Formulation and Evaluation of Extended-Release Solid Dispersion of Metformin Hydrochloridepp. 121–129
- Antioxidant, Antinociceptive and Anti-inflammatory Activities of Ethanolic Extract of Leaves of Alocasia indica (Schott.)pp. 137–14
- Glucagon Secreting Cells Responds to Insulin Secretion In vitro Using Immunocytochemistrypp. 144–147
Readers Also Viewed
Development and Validation of UV/visible Spectrophotometric Method for Estimation of Piroxicam from Bulk and Formulation
Sandip Mohan Honmane, Kunal Rajaram Yadav, Yuvraj Dilip Dange
Apr 23, 2025
Effects of Artificial Intelligence on Academic Performance of Library and Information Science University Students: A Meta-Analysis (2023-2025)
Kayode Sunday John Dada
Aug 6, 2026
Bridging Innovation and Impact: A Multidisciplinary Approach to Contemporary Research Challenges
Mueen Ahmed KK
Aug 11, 2026