Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia

Vinayaka, Anuhya; Sheshadri, Shubha; Madhyastha, Sharath P.; Shetty, Ganesh V.; Reddy, Charan Thej

doi:10.4103/jpp.JPP_29_20

Case ReportJournal of Pharmacology and PharmacotherapeuticsVol. 11 | Issue 4 | 2021 | pp. 140–141Open access

Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia

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²,
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¹ Department of Pharmacology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
² Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Correspondence: Sharath P. Madhyastha
Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Email: dr.sharathymc@gmail.com

Published:: May 14, 2021
Received:: Jun 7, 2020
Accepted:: Oct 21, 2020
DOI:: 10.4103/jpp.JPP_29_20

How to cite

Vinayaka, A., Sheshadri, S., Madhyastha, S. P., Shetty, G. V., & Reddy, C. T. (2021). Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia. Journal of Pharmacology and Pharmacotherapeutics, 11(4), 140–141. https://doi.org/10.4103/jpp.JPP_29_20

Abstract

Treatment of schizophrenia has taken so many turns, and adverse effects of the drugs still continue to remain as a hurdle in the management. Clozapine is considered to be the better promising drug in the treatment of paranoid schizophrenia with minimal side effects. Clozapine-induced agranulocytosis is one adverse event that troubles clinicians, and it requires a vigilant eye to look for the signs. In the present study, the authors discuss a case which has developed agranulocytosis in the later stages of clozapine treatment.

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Article metadata

Title	Late-Onset Clozapine-Induced Agranulocytosis in a Young Woman with Paranoid Schizophrenia
Authors	Anuhya Vinayaka; Shubha Sheshadri; Sharath P. Madhyastha; Ganesh V. Shetty; Charan Thej Reddy
Affiliations	Department of Pharmacology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.; Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Corresponding author	dr.sharathymc@gmail.com
Journal	Journal of Pharmacology and Pharmacotherapeutics
Volume / Issue	Vol. 11, Issue 4 (2021)