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Research LettersJournal of Pharmacology and PharmacotherapeuticsVol. 2 | Issue 4 | 2011 | pp. 285–287Open access
Effect of Erythrina variegata on experimental atherosclerosis in guinea pigs
- 1*,
- 2,
- 3
- 1 Faculty of Pharmacy, India.
- 2 Department of Pathology, Sri Ramachandra University, Porur, India.
- 3 Department of Chemistry, Captain Srinivasamurty Drug Research Institute for Ayurveda and Siddha, Arumbakkam, Chennai - 600 116, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Mangathayaru Kalachaveedu
Faculty of Pharmacy, India.
Email: kvmanga@yahoo.com
Copyright: © 2011 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Jan 1, 2011
How to cite
Kalachaveedu, M., Kuruvilla, S., & Balakrishna, K. (2011). Effect of Erythrina variegata on experimental atherosclerosis in guinea pigs. Journal of Pharmacology and Pharmacotherapeutics, 2(4), 285–287. https://doi.org/10.4103/0976-500X.85949
Abstract
Leaves of Erythrina variegata (Indian coral tree) (family: Fabaceae) eaten as a pot herb, are used as an antiobesity drug in Siddha medicine.[1] It has folkloric reputation as antiinflammatory in India, China and South East Asia, and different parts of the plant are reported with insecticidal, hemagglutinating, curaric, skeletal muscle relaxant, feeding deterrent, antispasmodic, antimycobacterial and antiosteoporotic activities.[2] In this study, the infl uence of the total alcohol extract of E. variegata (Ev) on experimental atherosclerosis in guinea pigs has been evaluated (IAEC approved, Ref: IAEC/SRMC and RI/41/2005). The extract was well tolerated, with no signs of toxicity up to 2 g/kg b.wt. in the acute toxicity study.
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Article metadata
| Title | Effect of Erythrina variegata on experimental atherosclerosis in guinea pigs |
|---|---|
| Authors | Mangathayaru Kalachaveedu; Sarah Kuruvilla; K. Balakrishna |
| Affiliations | Faculty of Pharmacy, India.; Department of Pathology, Sri Ramachandra University, Porur, India.; Department of Chemistry, Captain Srinivasamurty Drug Research Institute for Ayurveda and Siddha, Arumbakkam, Chennai - 600 116, India. |
| Corresponding author | kvmanga@yahoo.com |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 2, Issue 4 (2011) |
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