Open access · Peer reviewed · No APCs
Research LettersJournal of Pharmacology and PharmacotherapeuticsVol. 3 | Issue 1 | 2012 | pp. 60–61Open access
Antidepressant-like activity of Benincasa hispida fruits in mice: Possible involvement of monoaminergic and GABAergic systems
- 1*,
- 1
- 1 Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Dinesh Dhingra
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India.
Email: din_dhingra@rediffmail.com
Copyright: © 2012 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Jan 1, 2012
How to cite
Dhingra, D., & Joshi, P. (2012). Antidepressant-like activity of Benincasa hispida fruits in mice: Possible involvement of monoaminergic and GABAergic systems. Journal of Pharmacology and Pharmacotherapeutics, 3(1), 60–61. https://doi.org/10.4103/0976-500X.92520
Abstract
Depression is one of the major mental disorders affecting hundreds of millions of people all over the world. There is a constant need to identify newer antidepressants from plants. Benincasa hispida (Cucurbitaceae) fruits were selected for evaluating its antidepressant potential in mice. There is only one study showing the antidepressant-like effect of the methanolic extract (0.6 and 1 g/kg administered three times and only once, respectively) of B. hispida fruits in mouse forced swim test (FST). The study showed the antidepressant-like effect of the methanolic extract in FST only and the mechanisms responsible for this activity have not been studied.
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Article metadata
| Title | Antidepressant-like activity of Benincasa hispida fruits in mice: Possible involvement of monoaminergic and GABAergic systems |
|---|---|
| Authors | Dinesh Dhingra; Parul Joshi |
| Affiliations | Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India. |
| Corresponding author | din_dhingra@rediffmail.com |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 3, Issue 1 (2012) |
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