Open access · Peer reviewed · No APCs
News and ViewsJournal of Pharmacology and PharmacotherapeuticsVol. 3 | Issue 4 | 2012 | pp. 350–350Open access
One more option to void
- 1*
- 1 Department of Pharmacology, Indira Gandhi Medical College and.
- 2 Research Institute, Kadhirkamam, Puducherry, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Sivagnanam G
Department of Pharmacology, Indira Gandhi Medical College and.
Email: drsivagnanam@gmail.com
Copyright: © 2012 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Jan 1, 2012
How to cite
G, S. (2012). One more option to void. Journal of Pharmacology and Pharmacotherapeutics, 3(4), 350.
Abstract
Pendrin is expressed on the cells of distal convoluted tubule and the collecting duct. It is involved in Cl-/HCO3- exchange (mediates HCO3- secretion and Cl- absorption) and has been demonstrated to play an important role in compensatory salt absorption in response to thiazide and loop diuretics. It has been proposed that pharmacological inhibition of pendrin and thiazide- sensitive NaCl co-transporter can provide a novel and strong diuretic regimen in fluid overload conditions such as congestive heart failure, nephrotic syndrome, etc.
Keywords
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Article metadata
| Title | One more option to void |
|---|---|
| Authors | Sivagnanam G |
| Affiliations | Department of Pharmacology, Indira Gandhi Medical College and.; Research Institute, Kadhirkamam, Puducherry, India. |
| Corresponding author | drsivagnanam@gmail.com |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 3, Issue 4 (2012) |
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