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Case ReportJournal of Pharmacology and PharmacotherapeuticsVol. 7 | Issue 2 | 2016 | pp. 109–11Open access
Fixed drug eruption due to levocetirizine
- 1*,
- 2,
- 3
- 1 Departments of Pharmacology and Toxicology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
- 2 Department of Dermatology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
- 3 Department of Pharmacovigilance, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Ratinder Jhaj
Departments of Pharmacology and Toxicology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Email: rati.pharm@aiimsbhopal.edu.in
Copyright: © 2016 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Jan 1, 2016
- Received:
- Dec 15, 2015
- Accepted:
- May 21, 2016
How to cite
Jhaj, R., Asati, D. P., & Chaudhary, D. (2016). Fixed drug eruption due to levocetirizine. Journal of Pharmacology and Pharmacotherapeutics, 7(2), 109–11. https://doi.org/10.4103/0976-500X.184778
Abstract
A fixed drug eruption (FDE) is a cutaneous adverse drug reaction due to Type IV or delayed cell–mediated hypersensitivity. Antihistamines, which antagonize the action of histamine during an allergic reaction by blocking the H1 histamine receptors, are used routinely for the treatment of various allergic disorders such as urticaria, eczemas, and also in itchy lesions of skin like scabies.Levocetirizine, an active (R)‑enantiomer of cetirizine, is a newer or second generation antihistamine, with more specific actions and fewer side effects, including cutaneous reactions. FDE due to levocetirizine as well as with cetirizine are rare. We report a case of levocetirizine induced FDE in a 49‑year‑old male patient with scabies. The patient had a history of cetirizine induced FDE in the past.
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Subject
Article metadata
| Title | Fixed drug eruption due to levocetirizine |
|---|---|
| Authors | Ratinder Jhaj; Dinesh Prasad Asati; Deepa Chaudhary |
| Affiliations | Departments of Pharmacology and Toxicology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.; Department of Dermatology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.; Department of Pharmacovigilance, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India. |
| Corresponding author | rati.pharm@aiimsbhopal.edu.in |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 7, Issue 2 (2016) |
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