Open access · Peer reviewed · No APCs
Review ArticleJournal of Pharmacology and PharmacotherapeuticsVol. 9 | Issue 1 | 2018 | pp. 1–5Open access
The Blood Blues: A Review on Methemoglobinemia
- 1,
- 1,
- 1,
- 1*
- 1 PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Rajan Rajabalaya
PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam.
Email: rajanmpharm@gmail.com
Copyright: © 2018 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Jan 1, 2018
- Received:
- Jun 6, 2017
- Accepted:
- Dec 19, 2017
How to cite
David, S. R., Sawal, N. S., Hamzah, M. N. S. B., & Rajabalaya, R. (2018). The Blood Blues: A Review on Methemoglobinemia. Journal of Pharmacology and Pharmacotherapeutics, 9(1), 1–5. https://doi.org/10.4103/jpp.JPP_79_17
Abstract
Methemoglobinemia is a blood disorder in which there is an abnormal amount of methemoglobin (MetHb) formation, thus unable to release oxygen effectively to body tissues. This is mainly because MetHb is the altered state of hemoglobin (Hb) wherein the ferrous iron of heme has been oxidized to the ferric state. This review paper discusses in detail about the different types of methemoglobinemia and their causes with biochemical pathway and mechanisms. Patients with high MetHb in the blood will appear blue when they have cyanosis but can be cured with the methylene blue solution. However, a proper management should be laid out for strategic treatment. This review will be useful to health‑care providers, pharmacists, biochemists, and researchers to understand the basics of methemoglobinemia and its current treatment with guidelines. This review will benefit the readers to understand and will be a ready reference for methemoglobinemia.
Keywords
Subject
Article metadata
| Title | The Blood Blues: A Review on Methemoglobinemia |
|---|---|
| Authors | Sheba Rani David; Nora Syahirah Sawal; Muhammad Nur Salam Bin Hamzah; Rajan Rajabalaya |
| Affiliations | PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam. |
| Corresponding author | rajanmpharm@gmail.com |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 9, Issue 1 (2018) |
Also in this issue
- Drug Approval in India Does not Match the Disease Burden: A Cross‑sectional Studypp. 6–10
- Valproic Acid Reduces Tumor Cell Survival and Proliferation with Inhibitors of Downstream Molecules of Epidermal Growth Factor Receptor Pathwaypp. 11–6
- Effect of Etoksidol Against Sulfur-Containing Gas Induced Reduction in Bone Marrow Microcirculation in Different Stages of Ontogenesis in Ratspp. 17–20
- Effect of Coexisting Hypertension, Blood Pressure Control, and Antihypertensive Treatment on QT Interval Parameters in Type 2 Diabetics: A Cross‑Sectional Studypp. 21–26
- Efficacy and Safety of Nadifloxacin and Benzoyl Peroxide versus Adapalene and Benzoyl Peroxide in Acne Vulgaris: A Randomized Open‑label Phase IV Clinical Trialpp. 27–31
Readers Also Viewed
Development and Validation of UV/visible Spectrophotometric Method for Estimation of Piroxicam from Bulk and Formulation
Sandip Mohan Honmane, Kunal Rajaram Yadav, Yuvraj Dilip Dange
Apr 23, 2025
Effects of Artificial Intelligence on Academic Performance of Library and Information Science University Students: A Meta-Analysis (2023-2025)
Kayode Sunday John Dada
Aug 6, 2026
Bridging Innovation and Impact: A Multidisciplinary Approach to Contemporary Research Challenges
Mueen Ahmed KK
Aug 11, 2026