Open access · Peer reviewed · No APCs
Review ArticleJournal of Pharmacology and PharmacotherapeuticsVol. 9 | Issue 3 | 2018 | pp. 126–30Open access
Phosphodiesterase 7B1 as Therapeutic Target for Treatment of Cognitive Dysfunctions in Multiple Sclerosis
- 1*,
- 1
- 1 Department of Pharmacology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Arthi Balsundaram
Department of Pharmacology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.
Email: rtms86@yahoo.com
Copyright: © 2018 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Jan 1, 2018
- Received:
- Jun 11, 2018
- Accepted:
- Oct 12, 2018
How to cite
Balsundaram, A., & Chellathai, D. (2018). Phosphodiesterase 7B1 as Therapeutic Target for Treatment of Cognitive Dysfunctions in Multiple Sclerosis. Journal of Pharmacology and Pharmacotherapeutics, 9(3), 126–30. https://doi.org/10.4103/jpp.JPP_77_18
Abstract
Multiple sclerosis (MS) is an autoimmune, chronic degenerative neuroinflammatory disorder affecting younger age groups of the United States of America and Europe. MS prevalence studies in India have shown that India is no longer a low‑risk zone. Many studies have shown the seriousness of cognitive impairments (CIs) and its types caused in MS. In this review, the pathological basis for CI in various stages of MS was reviewed and revealed to provide a basis for the treatment. Role of phosphodiesterase 7B1 (PDE7B1) inhibitors in treating CI related to MS were also stated in this review. The literature for this review was collected from PubMed and Embase.
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Article metadata
| Title | Phosphodiesterase 7B1 as Therapeutic Target for Treatment of Cognitive Dysfunctions in Multiple Sclerosis |
|---|---|
| Authors | Arthi Balsundaram; Darling Chellathai |
| Affiliations | Department of Pharmacology, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India. |
| Corresponding author | rtms86@yahoo.com |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 9, Issue 3 (2018) |
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