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Research ArticlePharmacognosy ResearchVol. 1 | Issue 4 | 2009 | pp. 175–178Open access
Biological and Chemical Study of Cleome paradoxa B.Br.
- 1*,
- 2,
- 3
- 1 Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia
- 2 Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
- 3 Pharmacology Department, National Research Centre, Giza 12622, Egypt
Published in Pharmacognosy Research
Correspondence: Essam Abdel-Sattar
Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia
Email: abdelsattar@yahoo.com
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Apr 14, 2009
- Accepted:
- Jun 2, 2009
How to cite
Abdel-Sattar, E., El-Monem, A. R. A., & Sleem, A. A. (2009). Biological and Chemical Study of Cleome paradoxa B.Br. Pharmacognosy Research, 1(4), 175–178.
Abstract
The methanolic extract of Cleome paradoxa B.Br. and its different fractions (viz. hexane, chloroform, ethyl acetate and n-butanol) were tested for their antidiabetic activities. The ethyl acetate and hexane fractions exhibited the highest activities, which further subjected to chemical investigation. This study resulted in isolation of two compounds from the ethyl acetate fraction and three compounds from the hexane fraction. These compounds were identified using different spectroscopic methods as quercetin, quercetin-3-O-β-D-glucopyranoside (isoquercetrin), α-amyrin, sitgmasterol and sitgmasterol-3-O-β-D-glucpyranoside. The major compound isolated from ethyl acetate fraction, isoquercetrin, was assessed for its antidiabetic activity.
Keywords
Subject
Article metadata
| Title | Biological and Chemical Study of Cleome paradoxa B.Br. |
|---|---|
| Authors | Essam Abdel-Sattar; Azza R. Abd El-Monem; Amany A. Sleem |
| Affiliations | Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia; Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt; Pharmacology Department, National Research Centre, Giza 12622, Egypt |
| Corresponding author | abdelsattar@yahoo.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 1, Issue 4 (2009) |
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