Pharmaceutico-Analytical Assessment of Jeevanthyadi ghrita-A Polyherbal Ayurveda Formulation and its Potential Benefits

Background: Standardization and documentation of Traditional medicines have caught pace in recent past and yet remain a subject of discussion. Jeevanthyadi ghrita is a commonly prescribed empirically for debilitating health conditions. However, its pharmaceutical and analytical data remains untraced. Hence an attempt was made to prepare, screen the active biological constituents and review the recent activities of ingredients of the Jeevanthyadi ghirta to rationalize the classical indications. Results: Prepared Jeevanthyadi ghrita showed presence of Alkaloids and terpenoids. HPTLC analysis detected the presence of 7 and 11 active biological constituents at 254 nm and 366 nm respectively, which remains to be identified. No significant difference was noted between plain ghrita and prepared Jeevanthyadi ghrita in relation to AGMARK parameters. Conclusion: Recent activities of ingredients showed strong anti-inflammatory and immunomodulatory effect that has a relation to ceasing the pathology of debilitation.