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Original ArticlePharmacognosy ResearchVol. 2 | Issue 3 | 2010 | pp. 190–194Open access
The antihyperglycemic effect of aerial parts of Salvia splendens (scarlet sage) in streptozotocin-induced diabetic-rats
- 1*,
- 2,
- 2
- 1 GITAM Institute of Pharmacy, GITAM University, Visakhapatnam
- 2 Department of Pharmaceutical Sciences BIT, Mesra, Ranchi, India
Published in Pharmacognosy Research
Correspondence: P. Mahesh Kumar
GITAM Institute of Pharmacy, GITAM University, Visakhapatnam
Email: posa.mahesh@gmail.com
Copyright: © 2010 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2010
- Received:
- Jan 23, 2010
- Accepted:
- Jul 19, 2010
How to cite
Kumar, P. M., Sasmal, D., & Mazumder, P. M. (2010). The antihyperglycemic effect of aerial parts of Salvia splendens (scarlet sage) in streptozotocin-induced diabetic-rats. Pharmacognosy Research, 2(3), 190–194. https://doi.org/10.4103/0974-8490.65520
Abstract
Salvia splendens (Labiatae) is widely used in Indian traditional medicine for the control of diabetes mellitus. In this study, the hypoglycemic effects produced by the acute and subacute administration of various extracts of S. splendens were investigated. Both the aqueous extract (SSAE) and the methanolic extract (SSME) from the aerial parts resulted in significant reductions of glycemia in streptozotocin (STZ)-induced diabetic rats after oral administration at a dose of 100 and 200 mg/ kg, respectively. On oral administration, aqueous and methanolic extracts showed statistically significant (P < 0.001) effect by reducing the effect of glycemia in STZ-induced diabetic rats. These findings suggest the significant antihyperglycemic potential of the S. splendens extracts in ameliorating the diabetic conditions in diabetic rats. No significant effects were found in the normal rats.
Keywords
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Article metadata
| Title | The antihyperglycemic effect of aerial parts of Salvia splendens (scarlet sage) in streptozotocin-induced diabetic-rats |
|---|---|
| Authors | P. Mahesh Kumar; D. Sasmal; Papiya Mitra Mazumder |
| Affiliations | GITAM Institute of Pharmacy, GITAM University, Visakhapatnam; Department of Pharmaceutical Sciences BIT, Mesra, Ranchi, India |
| Corresponding author | posa.mahesh@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 2, Issue 3 (2010) |
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