Open access · Peer reviewed · No APCs
ORIGINAL ARTICLEPharmacognosy ResearchVol. 7 | Issue 1 | 2015 | pp. 45–48Open access
Cycloolivil, a lignan from the roots of Stereospermum suaveolens
- 1,
- 2*,
- 2,
- 2,
- 2,
- 2
- 1 Pharmacognosy, Government College of Pharmacy
- 2 Departments of Phytochemistry, Natural Remedies Pvt. Ltd. Bangalore, Karnataka, India
Published in Pharmacognosy Research
Correspondence: Janani Jacob
Departments of Phytochemistry, Natural Remedies Pvt. Ltd. Bangalore, Karnataka, India
Email: janani@naturalremedy.com
Copyright: © 2015 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2015
How to cite
Sab, B. A. W., Jacob, J., Manjunath, G. G., Singh, V. K., Mundkinajeedu, D., & Shankarappa, S. (2015). Cycloolivil, a lignan from the roots of Stereospermum suaveolens. Pharmacognosy Research, 7(1), 45–48. https://doi.org/10.4103/0974-8490.147198
Abstract
Background
Stereospermum suaveolens DC. (Syn. S. chelonoides) belonging to family Bignoniaceae is an important medicinal plant in India. Traditionally, it is mainly used as analgesic, liver stimulant, astringent, wound healing and antidyspeptic. Roots of this plant are one of the ingredients of Dashamularishta. The plant has been studied for many pharmacological actions, only few were concerned with isolation of active compounds.
Objective
The present work deals with the isolation and identification of phytochemical constituents present in the roots of Stereospermum suaveolens.
Material and Methods
The compounds were isolated from the ethyl acetate-soluble fraction from the methanol extract of S. suaveolens by using open silica gel column chromatography and HPLC was carried out for all the fractions to target the major peaks in fractions.
Results and Conclusion
The isolated compounds structures were elucidated by analysis of spectroscopic data (UV, IR, 1D-NMR, and MS) and characterized as Cycloolivil (1) reported for the first time from this plant species, Lapachol (2) and b-sitosterol (3), respectively.
Keywords
Subject
Article metadata
| Title | Cycloolivil, a lignan from the roots of Stereospermum suaveolens |
|---|---|
| Authors | B. Abdul wahab Sab; Janani Jacob; Gururaja Giligar Manjunath; Vineet Kumar Singh; Deepak Mundkinajeedu; Shashidhara Shankarappa |
| Affiliations | Pharmacognosy, Government College of Pharmacy; Departments of Phytochemistry, Natural Remedies Pvt. Ltd. Bangalore, Karnataka, India |
| Corresponding author | janani@naturalremedy.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 7, Issue 1 (2015) |
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