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Original ArticlePharmacognosy MagazineVol. 17 | Issue 74 | 2021 | pp. 263–267Open access
In silico Studies on the Therapeutic Potential of Novel Marker Compounds Isolated from Chemically Modified Bioactive Fraction from Curcuma longa (Non-carbonyl Curcuma longa)
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- 1 Department of Chemistry, College of Science, Taibah University, Al‑Madina Al‑Munawwara, Saudi Arabia.
- 2 Pharmaceutics Division, CSIR‑Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
- 3 Vitamins, The National Organization for Drug Control and Research, Al‑Agouzah, Giza, Egypt.
Published in Pharmacognosy Magazine
Correspondence: Arshi Naqvi
Pharmaceutics Division, CSIR‑Central Drug Research Institute, Lucknow, Uttar Pradesh, India.; Vitamins, The National Organization for Drug Control and Research, Al‑Agouzah, Giza, Egypt.
Email: arshi_84@yahoo.com
Copyright: © 2021 Manuscript Technomedia. This is an open access article.
- Published:
- Jul 12, 2021
- Received:
- Jul 31, 2020
- Accepted:
- Dec 3, 2020
- DOI:
- 10.4103/pm.pm_317_20
How to cite
Naqvi, A., Al‑Harbi, R. A. K., Ali, S., Malasoni, R., Gupta, S., & Dwivedi, A. K. (2021). In silico Studies on the Therapeutic Potential of Novel Marker Compounds Isolated from Chemically Modified Bioactive Fraction from Curcuma longa (Non-carbonyl Curcuma longa). Pharmacognosy Magazine, 17(74), 263–267. https://doi.org/10.4103/pm.pm_317_20
Abstract
Objectives: In the present study, novel marker compounds (A and B) have been successfully isolated from NCCL and their various in silico traits and interactions were studied. Materials and Methods: Marker compounds A and B were characterized utilizing various spectroscopic data (one‑dimensional [1D]/2D Nuclear Magnetic Resonance (NMR), mass spectrometry, and infrared). Isolated compounds were subjected to in silico computational tools for predicting their drug‑likeness, pharmacokinetic, pharmacodynamic properties. Results: Both compounds A and B flaunted drug‑like properties by following the standard descriptors along with good in silico absorption. Conclusion: Novel marker compounds A and B were successfully isolated from NCCL and fully characterized utilizing spectroscopic techniques. Both the compounds displayed good drug‑like properties.
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Article metadata
| Title | In silico Studies on the Therapeutic Potential of Novel Marker Compounds Isolated from Chemically Modified Bioactive Fraction from Curcuma longa (Non-carbonyl Curcuma longa) |
|---|---|
| Authors | Arshi Naqvi; Reem A. K. Al‑Harbi; Samah Ali; Richa Malasoni; Swati Gupta; Anil Kumar Dwivedi |
| Affiliations | Department of Chemistry, College of Science, Taibah University, Al‑Madina Al‑Munawwara, Saudi Arabia.; Pharmaceutics Division, CSIR‑Central Drug Research Institute, Lucknow, Uttar Pradesh, India.; Vitamins, The National Organization for Drug Control and Research, Al‑Agouzah, Giza, Egypt. |
| Corresponding author | arshi_84@yahoo.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 17, Issue 74 (2021) |
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