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ORIGINAL ARTICLEPharmacognosy ResearchVol. 7 | Issue 1 | 2015 | pp. 81–84Open access
Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity
- 1,
- 2*,
- 1,
- 2,
- 2
- 1 Department of Pharmacognosy, National College of Pharmacy
- 2 Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka, India
Published in Pharmacognosy Research
Correspondence: B. Thippeswamy
Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka, India
Email: thippeswamyb205@gmail.com
Copyright: © 2015 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2015
How to cite
Kumar, M. L. V., Thippeswamy, B., Kuppust, I. L., Naveenkumar, K. J., & Shivakumar, C. K. (2015). Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity. Pharmacognosy Research, 7(1), 81–84. https://doi.org/10.4103/0974-8490.147213
Abstract
Objective
To assess the anthelmintic acivity of Bacillus cereus and Bacillus pumilus metabolites.
Materials and Methods
The successive solvent extractions with petroleum ether, ethyl acetate and methanol. The solvent extracts were tested for anthelmintic activity against Pheretima posthuma at 20 mg/ml concentration. The time of paralysis and time of death of the worms was determined for all the extracts. Albendazole was taken as a standard reference and sterile water as a control.
Results
All the sample extracts showed significant anthelmintic activity in paralyzing the worms comparable with that of the standard drug. The time of death exhibited by BP metabolites was close to the time exhibited by standard.
Conclusion
The study indicates both bacteria Bacillus cereus and Bacillus pumilus have anthelmintic activity indicating potential metabolites in them.
Keywords
Subject
Article metadata
| Title | Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity |
|---|---|
| Authors | M. L. Vijaya Kumar; B. Thippeswamy; I. L. Kuppust; K. J. Naveenkumar; C. K. Shivakumar |
| Affiliations | Department of Pharmacognosy, National College of Pharmacy; Department of Microbiology, Kuvempu University, Shankarghatta, Shimoga, Karnataka, India |
| Corresponding author | thippeswamyb205@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 7, Issue 1 (2015) |
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