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Original ArticlePharmacognosy ResearchVol. 8 | Issue 4 | 2016 | pp. 281–286Open access
Elucidation of Flavonoids from Carissa congesta, Polyalthia longifolia, and Benincasa hispida Plant Extracts by Hyphenated Technique of Liquid Chromatography-mass Spectroscopy
- 1,4*,
- 1,
- 2,
- 1,
- 1,
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- 1 Departments of Pharmacology and Pharmaceutical Chemistry
- 2 Departments of Quality Assurance
- 3 Pharmaceutical Chemistry, Vivekanand Education Society’s College of Pharmacy, Mumbai, Maharashtra
- 4 Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan
- 5 Department of Pharmacology, Y. B. Chavan College of Pharmacy, Rouzabagh, Aurangabad, India
Published in Pharmacognosy Research
Correspondence: Gaurav M. Doshi
Departments of Pharmacology and Pharmaceutical Chemistry; Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan
Email: gaurav.pharmacology@gmail.com
Copyright: © 2016 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2016
How to cite
Doshi, G. M., Nalawade, V. V., Mukadam, A. S., Chaskar, P. K., Zine, S. P., Somani, R. R., & Une, H. D. (2016). Elucidation of Flavonoids from Carissa congesta, Polyalthia longifolia, and Benincasa hispida Plant Extracts by Hyphenated Technique of Liquid Chromatography-mass Spectroscopy. Pharmacognosy Research, 8(4), 281–286. https://doi.org/10.4103/0974-8490.186578
Abstract
Background
Carissa congesta (CC), Polyalthia longifolia (PL), and Benincasa hispida (BH) are economically important plants.
Objective
Current research encompasses identification of quercetin and rutin and their analogues by liquid chromatography-mass spectroscopy (LC-MS) from the selected plant species.
Materials and Methods
Fresh roots, leaves, and seeds of CC, PL, and BH plants respectively were shade-dried followed by extraction and elucidation of rutin and quercetin by LC-MS.
Results
Structural elucidation of CC, PL, and BH extracts revealed the presence of flavonoids such as quercetin (m/z 301) and rutin (m/z 610) as the parent ions along with presence of close analogues such as quercetin-O-hexoside, Vicenin 2, quercetin-3-O-xyloside/arabinoside, and quercetin-3-O-glucoside were identified as fragments.
Conclusions
Thus, CC, PL, and BH extracts revealed the presence of flavonoids belonging to the class of flavonols such as rutin and quercetin.
Keywords
Subject
Article metadata
| Title | Elucidation of Flavonoids from Carissa congesta, Polyalthia longifolia, and Benincasa hispida Plant Extracts by Hyphenated Technique of Liquid Chromatography-mass Spectroscopy |
|---|---|
| Authors | Gaurav M. Doshi; Vivek V. Nalawade; Aaditi S. Mukadam; Pratip K. Chaskar; Sandeep P. Zine; Rakesh R. Somani; Hemant D. Une |
| Affiliations | Departments of Pharmacology and Pharmaceutical Chemistry; Departments of Quality Assurance; Pharmaceutical Chemistry, Vivekanand Education Society’s College of Pharmacy, Mumbai, Maharashtra; Pacific Academy of Higher Education and Research University, Udaipur, Rajasthan; Department of Pharmacology, Y. B. Chavan College of Pharmacy, Rouzabagh, Aurangabad, India |
| Corresponding author | gaurav.pharmacology@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 8, Issue 4 (2016) |
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