Chemistry and Pharmacology of Picrorhiza Kurroa Royle ex Benth.

Picrorhiza kurroa, commonly known as kutki, is having a remarkable reputation among the indigenous medical practitioners. It is well-known in the Ayurveda and has traditionally been used to treat disorders of the liver and upper respiratory tract. Recent studies proved the plant to be efficacious in various diseases and have good potential to reach clinic. These studies are focussed on the hepatoprotective, anti-cholestic, antioxidant and immunomodulatory activity. The present article comprises a review of the chemical constituents and pharmacological actions of the plant to emphasise its importance in medicine.