Procyanidins from the bark of Prunus africana

Qa'dan, F.

Research ArticlePharmacognosy MagazineVol. 1 | Issue 4 | 2005 | pp. 152–154Open access

Procyanidins from the bark of Prunus africana

¹^*

¹ School of Pharmacy, The University of Petra, P.O.Box: 961343, Amman, 11196 Jordan, Jordan.

Correspondence: F. Qa'dan
School of Pharmacy, The University of Petra, P.O.Box: 961343, Amman, 11196 Jordan, Jordan.
Email: f_qadan@yahoo.com

Published:: Jan 1, 2005

How to cite

Qa'dan, F. (2005). Procyanidins from the bark of Prunus africana. Pharmacognosy Magazine, 1(4), 152–154.

Abstract

From the aqueous acetone extract of the bark of Prunus africana (Hook.f.) Kalkman (Syn. Pygeum africanum Hook.f.) the flavanols catechin (1) and epicatechin (2), and the procyanidins B-1 (3), B-2 (4), B-3 (5), A-2 (6) and C-1 (7) were isolated and identified. Their structures were established as their peracetate derivatives, on the basis of chemical and spectral evidence. The 13C-NMR spectrum of the higher molecular weight polymer fraction revealed a 3',4'-dihydroxylated B-ring oxidation pattern and the 2,3-cis relative stereochemistry of the constituent flavan-3-ol units. The mean average molecular size of the polymers was estimated to be about 8 to 9 flavan-3-ol-units.

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Article metadata

Title	Procyanidins from the bark of Prunus africana
Authors	F. Qa'dan
Affiliations	School of Pharmacy, The University of Petra, P.O.Box: 961343, Amman, 11196 Jordan, Jordan.
Corresponding author	f_qadan@yahoo.com
Journal	Pharmacognosy Magazine
Volume / Issue	Vol. 1, Issue 4 (2005)