Open access · Peer reviewed · No APCs
ORIGINAL ARTICLEPharmacognosy MagazineVol. 10 | Issue 37s | 2014 | pp. S57–S58Open access
Optimization of quercitrin and total flavonoids extraction from Herba Polygoni Capitati by response surface methodology
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- 1 The Research Center for Quality Control of Nature Medicine, Guizhou Nomal University, Guiyang, Guizhou, P.R. China, China.
- 2 Key Laboratory for Information System of Mountainous Area and Protection of Ecological Environment of Guizhou province, Guizhou Nomal University, Guiyang, Guizhou, P.R. China, China.
- 3 Guizhou Warmen Pharmaceutical Co., Ltd., Guiyang, Guizhou, P.R. China, China.
Published in Pharmacognosy Magazine
Correspondence: Xin Zhou
The Research Center for Quality Control of Nature Medicine, Guizhou Nomal University, Guiyang, Guizhou, P.R. China, China.; Key Laboratory for Information System of Mountainous Area and Protection of Ecological Environment of Guizhou province, Guizhou Nomal University, Guiyang, Guizhou, P.R. China, China.
Email: alice9800@sina.com
Copyright: © 2014 Manuscript Technomedia. This is an open access article.
- Published:
- Feb 21, 2014
- Received:
- Apr 11, 2013
- Accepted:
- Jun 8, 2013
How to cite
Ma, F., Zhao, Y., Gong, X., Xie, Y., & Zhou, X. (2014). Optimization of quercitrin and total flavonoids extraction from Herba Polygoni Capitati by response surface methodology. Pharmacognosy Magazine, 10(37s), S57–S58. https://doi.org/10.4103/0973-1296.127343
Abstract
Objective: To optimize the conditions for extraction of quercitrin and total flavonoids (TF) from Herba Polygoni Capitati (Touhualiao in Chinese) by using response surface methodology (RSM). Materials and Methods: A central composite design (CCD) was adopted to investigate the effects of three independent variables including solvent composition (%), solvent-material ratio (ml/g) and extraction time (min) on the responses, quercitrin and TF yields. Results: The optimized conditions of the extraction are as follows: Ethanol concentration, 65.63%; solvent-material ratio, 10.55:1 (ml/g); extraction time, 54.33 min. The established mathematical model described the factors of experimental parameters well and provided a statistically accurate prediction of the optimum yields of quercitrin and TF. Conclusion: The experimental values agreed with those predicted by the established mathematical model, thus indicating the suitability of the model employed and the success of RSM in optimizing the extraction conditions.
Keywords
Subject
Article metadata
| Title | Optimization of quercitrin and total flavonoids extraction from Herba Polygoni Capitati by response surface methodology |
|---|---|
| Authors | Fengwei Ma; Yang Zhao; Xiaojian Gong; Yu Xie; Xin Zhou |
| Affiliations | The Research Center for Quality Control of Nature Medicine, Guizhou Nomal University, Guiyang, Guizhou, P.R. China, China.; Key Laboratory for Information System of Mountainous Area and Protection of Ecological Environment of Guizhou province, Guizhou Nomal University, Guiyang, Guizhou, P.R. China, China.; Guizhou Warmen Pharmaceutical Co., Ltd., Guiyang, Guizhou, P.R. China, China. |
| Corresponding author | alice9800@sina.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 10, Issue 37s (2014) |
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