Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy MagazineVol. 11 | Issue 42 | 2015 | pp. 381–388Open access
Effects of Valerianae Radix et Rhizoma extract on psychological stress in mice
- 1,
- 2,
- 3*
- 1 Department of Health Service and Population Research, Institute of Psychiatry, King's College of London, London, UK.
- 2 Department of Sport Science, College of Sport Science, Pusan National University.
- 3 Department of Korean Medicine, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, Republic of Korea.
Published in Pharmacognosy Magazine
Correspondence: Su-In Cho
Department of Korean Medicine, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, Republic of Korea.
Email: sicho@pusan.ac.kr
Copyright: © 2015 Manuscript Technomedia. This is an open access article.
- Published:
- Mar 12, 2015
- Received:
- Apr 7, 2014
How to cite
Kim, J. S., Ahn, J. D., & Cho, S. I. (2015). Effects of Valerianae Radix et Rhizoma extract on psychological stress in mice. Pharmacognosy Magazine, 11(42), 381–388. https://doi.org/10.4103/0973-1296.153093
Abstract
Background: The aim of this study was to identify the effects of Valerianae Radix et Rhizoma water extract (VRe) originated from Valeriana fauriei Briquet on reducing psychological stress (PS) on mice. Objective: Mice were put under PS with communication box method: Restraining mice and forcing to see other mice underfoot shock stress. Materials and Methods: Measurements on plasma corticosterone, noradrenaline and lipid peroxidation, and elevated plus-maze (EPM) tests were carried out to determine the effect of VRe administration on physiological and behavioral responses of mice. Results: VRe showed anxiolytic effects in plasma corticosterone, noradrenaline, and EPM transfer latency levels, but it did not show any significant effects on the other indicators. Conclusion: V. fauriei, which has been used as a natural anxiolytic drug, exerts positive effects in the communication box induced PS in mice.
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Article metadata
| Title | Effects of Valerianae Radix et Rhizoma extract on psychological stress in mice |
|---|---|
| Authors | Jeong Suk Kim; Jeong Deok Ahn; Su-In Cho |
| Affiliations | Department of Health Service and Population Research, Institute of Psychiatry, King's College of London, London, UK.; Department of Sport Science, College of Sport Science, Pusan National University.; Department of Korean Medicine, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, Republic of Korea. |
| Corresponding author | sicho@pusan.ac.kr |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 11, Issue 42 (2015) |
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