Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy MagazineVol. 15 | Issue 60 | 2019 | pp. 18–23Open access
Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract
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- 1 Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.
- 2 National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Published in Pharmacognosy Magazine
Correspondence: Shuangshuang Qin
Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.
Email: qin_double@126.com
Copyright: © 2019 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 23, 2019
- Received:
- Jun 19, 2018
- Accepted:
- Nov 15, 2018
- DOI:
- 10.4103/pm.pm_317_18
How to cite
Chen, X., Qin, S., Li, C., Wu, Q., Jiang, C., Yang, J., Guo, X., & Ou, C. (2019). Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract. Pharmacognosy Magazine, 15(60), 18–23. https://doi.org/10.4103/pm.pm_317_18
Abstract
Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> (CQ) is a well-known medicinal plant used in traditional medicine for bone healing. Objective: The present study was aimed to evaluate the anti-inflammatory and antioxidant activities of the methanolic extract of <em>Cissus quadrangularis</em> stem (MECQ). Materials and Methods: The anti-inflammatory activity was evaluated using the carrageenan-induced rat paw edema model. The antioxidant activity was assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay, and total phenolic content (TPC) determination. Results: MECQ showed significant anti-inflammatory activity in a dose-dependent manner. It also exhibited potent antioxidant activity with high TPC. Conclusion: The results suggest that MECQ possesses significant anti-inflammatory and antioxidant activities, which may be attributed to the presence of phenolic compounds.
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Article metadata
| Title | Evaluation of Anti-inflammatory and Antioxidant Activities of Cissus quadrangularis Stem Extract |
|---|---|
| Authors | Xiaoying Chen; Shuangshuang Qin; Cui Li; Qinghua Wu; Chao Jiang; Jian Yang; Xiaoyun Guo; Chunli Ou |
| Affiliations | Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, China.; National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China. |
| Corresponding author | qin_double@126.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 15, Issue 60 (2019) |
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