Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy MagazineVol. 16 | Issue 67 | 2020 | pp. 21–26Open access
Dietary Supplementation of Hemidesmus indicus and Swimming Exercise Attenuates Oxidative Stress in the Rat Brain
- 1*,
- 1,
- 2,
- 1
- 1 Ravikiran Tekupalli Department of Biotechnology, Bangalore University, India.
- 2 Department of Biotechnology and Genetics, Ramaiah College of Arts Science and Commerce, Bengaluru, Karnataka, India.
Published in Pharmacognosy Magazine
Correspondence: Bhagyalakshmi Dundaiah
Ravikiran Tekupalli Department of Biotechnology, Bangalore University, India.
Email: ravikiran@bub.ernet.in
Copyright: © 2020 Manuscript Technomedia. This is an open access article.
- Published:
- Feb 11, 2020
- Received:
- Jun 2, 2019
- Accepted:
- Aug 20, 2019
- DOI:
- 10.4103/pm.pm_239_19
How to cite
Dundaiah, B., Kariyappa, A. S., Ramachandregowda, S., & Anand, S. (2020). Dietary Supplementation of Hemidesmus indicus and Swimming Exercise Attenuates Oxidative Stress in the Rat Brain. Pharmacognosy Magazine, 16(67), 21–26. https://doi.org/10.4103/pm.pm_239_19
Abstract
Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored. Objective: To evaluate the antioxidant and anti-inflammatory activities of <em>Cissus arnottiana</em>. Materials and Methods: The methanolic extract of <em>C. arnottiana</em> leaves was evaluated for antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), nitric oxide, and hydroxyl radical scavenging assays. Anti-inflammatory activity was assessed using the carrageenan-induced rat paw edema model. Results: The extract showed significant antioxidant activity in a dose-dependent manner. In the anti-inflammatory assay, the extract at 200 and 400 mg/kg doses significantly reduced paw edema compared to the control group. Conclusion: <em>C. arnottiana</em> possesses significant antioxidant and anti-inflammatory activities, supporting its traditional use.
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Article metadata
| Title | Dietary Supplementation of Hemidesmus indicus and Swimming Exercise Attenuates Oxidative Stress in the Rat Brain |
|---|---|
| Authors | Bhagyalakshmi Dundaiah; Anupama Sindhaghatta Kariyappa; Sowbhagya Ramachandregowda; Santosh Anand |
| Affiliations | Ravikiran Tekupalli Department of Biotechnology, Bangalore University, India.; Department of Biotechnology and Genetics, Ramaiah College of Arts Science and Commerce, Bengaluru, Karnataka, India. |
| Corresponding author | ravikiran@bub.ernet.in |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 16, Issue 67 (2020) |
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