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Research ArticlePharmacognosy MagazineVol. 4 | Issue 13 | 2008 | pp. 27–28Open access
Effects of an extract of Cissampelos pareira on the hemorrhagic and proteolytic activities from Bothrops asper venom
- 1*,
- 2*,
- 1,
- 1,
- 3*
- 1 INIFAR, Facultad de Farmacia, Universidad de Costa Rica, San José, Costa Rica.
- 2 Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
- 3 Facultad de Ciencias Ambientales, Universidad Nacional de Costa Rica. Heredia, Costa Rica.
Published in Pharmacognosy Magazine
Correspondence: B. Badilla
INIFAR, Facultad de Farmacia, Universidad de Costa Rica, San José, Costa Rica.
Email: bbadilla@cariari.ucr.ac.cr
Correspondence: F. Chaves
Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.
Email: fchaves@icp.ucr.ac.cr
Correspondence: L.J. Poveda
Facultad de Ciencias Ambientales, Universidad Nacional de Costa Rica. Heredia, Costa Rica.
Email: lpoveda@una.ac.cr
Copyright: © 2008 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2008
How to cite
Badilla, B., Chaves, F., Jiménez, S., Rodríguez, G., & Poveda, L. (2008). Effects of an extract of Cissampelos pareira on the hemorrhagic and proteolytic activities from Bothrops asper venom. Pharmacognosy Magazine, 4(13), 27–28.
Abstract
The capacity of an aqueous extract from leaves of Cissampelos pareira to neutralize the hemorrhagic and proteolytic activities of the venom of Bothrops asper was evaluated. To establish the anti-hemorrhagic activity, the skin of mice was injected with a mixture of extract and venom, and it was found that extract produced a total inhibition of this activity. On the other hand, experiments regarding the anti-proteolytic activity were conducted observing the effect on casein in a test tube or on biotinylated casein in a microplate. None of the two procedures was able to show any inhibitory activity.
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Article metadata
| Title | Effects of an extract of Cissampelos pareira on the hemorrhagic and proteolytic activities from Bothrops asper venom |
|---|---|
| Authors | B. Badilla; F. Chaves; S. Jiménez; G. Rodríguez; L.J. Poveda |
| Affiliations | INIFAR, Facultad de Farmacia, Universidad de Costa Rica, San José, Costa Rica.; Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.; Facultad de Ciencias Ambientales, Universidad Nacional de Costa Rica. Heredia, Costa Rica. |
| Corresponding author | bbadilla@cariari.ucr.ac.cr |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 4, Issue 13 (2008) |
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